ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	SUGT1
Symbol Alias	SGT1
Approved Name	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
Location	13q12.2-q13.3
Position	chr13:53226831-53262433, +
External Links	HGNC: 16987 Entrez Gene: 10910 Ensembl: ENSG00000165416 UCSC: uc001vhc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 45)

Literature-origin SNPs (count: 0)

LD-proxies (count: 45)

rs_ID	Location	Functional Annotation
rs6561674	Chr13:53226473(Fwd)	upstream_gene_variant
rs7335091	Chr13:53231454(Fwd)	intron_variant; nc_transcript_variant
rs2118093	Chr13:53227840(Fwd)	intron_variant; nc_transcript_variant
rs2408657	Chr13:53262175(Fwd)	3_prime_UTR_variant; downstream_gene_variant
rs8000715	Chr13:53228119(Fwd)	intron_variant; nc_transcript_variant
rs1898282	Chr13:53265418(Fwd)	downstream_gene_variant
rs9536222	Chr13:53229017(Fwd)	intron_variant; nc_transcript_variant
rs7319451	Chr13:53222464(Fwd)	downstream_gene_variant; upstream_gene_variant
rs6561673	Chr13:53226444(Fwd)	upstream_gene_variant
rs7329993	Chr13:53226628(Fwd)	upstream_gene_variant
rs7335270	Chr13:53240121(Fwd)	downstream_gene_variant; intron_variant
rs9526970	Chr13:53240546(Fwd)	downstream_gene_variant; intron_variant
rs9536228	Chr13:53246054(Fwd)	intron_variant
rs9536232	Chr13:53247700(Fwd)	intron_variant
rs4542538	Chr13:53232489(Fwd)	intron_variant; nc_transcript_variant
rs4885804	Chr13:53236381(Fwd)	intron_variant; nc_transcript_variant
rs9526966	Chr13:53238843(Fwd)	intron_variant; nc_transcript_variant
rs6561677	Chr13:53238983(Fwd)	intron_variant; nc_transcript_variant
rs7987405	Chr13:53253938(Fwd)	intron_variant
rs971513	Chr13:53253286(Fwd)	intron_variant
rs9316583	Chr13:53254639(Fwd)	intron_variant
rs9536235	Chr13:53254497(Fwd)	intron_variant
rs7996692	Chr13:53251733(Fwd)	intron_variant
rs7999466	Chr13:53249219(Fwd)	intron_variant
rs4884223	Chr13:53252306(Fwd)	intron_variant
rs7995188	Chr13:53251766(Fwd)	intron_variant
rs1036452	Chr13:53263266(Fwd)	downstream_gene_variant
rs9526978	Chr13:53258173(Fwd)	intron_variant
rs2033684	Chr13:53266285(Fwd)	downstream_gene_variant
rs2033685	Chr13:53266210(Fwd)	downstream_gene_variant
rs7330193	Chr13:53256830(Fwd)	intron_variant
rs7330361	Chr13:53256798(Fwd)	intron_variant
rs9536238	Chr13:53257693(Fwd)	intron_variant
rs4885910	Chr13:53257498(Fwd)	intron_variant
rs7330755	Chr13:53264457(Fwd)	downstream_gene_variant
rs1436725	Chr13:53267206(Fwd)	downstream_gene_variant
rs4885887	Chr13:53252726(Fwd)	intron_variant
rs4539485	Chr13:53254082(Fwd)	intron_variant
rs9316581	Chr13:53245178(Fwd)	intron_variant
rs973198	Chr13:53250839(Fwd)	intron_variant
rs1436728	Chr13:53228460(Fwd)	intron_variant; nc_transcript_variant
rs9526976	Chr13:53255948(Fwd)	intron_variant
rs7325840	Chr13:53251087(Fwd)	intron_variant
rs6561676	Chr13:53238834(Fwd)	intron_variant; nc_transcript_variant
rs9568747	Chr13:53234583(Fwd)	intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000776	kinetochore	Cellular Component	TAS[10445024]	15
GO:0005634	nucleus	Cellular Component		770
GO:0000151	ubiquitin ligase complex	Cellular Component	TAS[10445024]	15
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	Biological Process		8
GO:0045087	innate immune response	Biological Process		54
GO:0005829	cytosol	Cellular Component		447
GO:0007067	mitosis	Biological Process	TAS[10445024]	39

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04621	NOD-like receptor signaling pathway	16	Specific families of pattern recognition receptors are respo...... Specific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains more than 20 members in mammals and plays a pivotal role in the recognition of intracellular ligands. NOD1 and NOD2, two prototypic NLRs, sense the cytosolic presence of the bacterial peptidoglycan fragments that escaped from endosomal compartments, driving the activation of NF-{kappa}B and MAPK, cytokine production and apoptosis. On the other hand, a different set of NLRs induces caspase-1 activation through the assembly of multiprotein complexes called inflammasomes. These NLRs include NALP1, NALP3 and Ipaf. The inflammasomes are critical for generating mature proinflammatory cytokines in concert with Toll-like receptor signaling pathway. More...

Genes shared at least 5 GO terms with SUGT1 (count: 0)

Genes shared at least 2 KEGG pathways with SUGT1 (count: 0)

View in gBrowse

Region: chr13:53226831..53262433 View in gBrowse