ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RNF125
Symbol Alias	FLJ20456
Approved Name	ring finger protein 125
Location	18q12.1
Position	chr18:29598335-29653176, +
External Links	HGNC: 21150 Entrez Gene: 54941 Ensembl: ENSG00000101695 UCSC: uc002kxf.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 5)

ID	Name	Type	No. of Genes in ADHDgene
GO:0045087	innate immune response	Biological Process	54
GO:0008270	zinc ion binding	Molecular Function	323
GO:0032480	negative regulation of type I interferon production	Biological Process	10
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	52
GO:0005622	intracellular	Cellular Component	67

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04622	RIG-I-like receptor signaling pathway	10	Specific families of pattern recognition receptors are respo...... Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helicases termed RIG-I-like receptors (RLRs). The RLR proteins include RIG-I, MDA5, and LGP2 and are expressed in both immune and nonimmune cells. Upon recognition of viral nucleic acids, RLRs recruit specific intracellular adaptor proteins to initiate signaling pathways that lead to the synthesis of type I interferon and other inflammatory cytokines, which are important for eliminating viruses. More...

Genes shared at least 5 GO terms with RNF125 (count: 0)

Genes shared at least 2 KEGG pathways with RNF125 (count: 0)

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Region: chr18:29598335..29653176 View in gBrowse