ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007267
Name	cell-cell signaling
Type	Biological Process
No. of Genes in ADHDgene	38
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 9)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
EREG	epiregulin	4q21.21	1(0/0/1)	IDA[14581411]
ADRA1A	adrenergic, alpha-1A-, receptor	8p21.2	3(2/1/0)	TAS[8396931]
ADRA1D	adrenergic, alpha-1D-, receptor	20p13	1(0/1/0)	TAS[1656955]
NTF3	neurotrophin 3	12p13	3(1/2/0)	TAS[2236018]
FADS1	fatty acid desaturase 1	11q12-q13.1	3(1/2/0)	NAS[10601301]
ADRA2B	adrenergic, alpha-2B-, receptor	2q11.1	1(1/0/0)	TAS[2164221]
GPR50	G protein-coupled receptor 50	Xq28	1(0/0/1)	TAS[8647286]
ADRA2C	adrenergic, alpha-2C-, receptor	4p16.3	7(2/4/1)	TAS[9371698]
ADRA1B	adrenergic, alpha-1B-, receptor	5q33.3	2(1/1/0)	TAS[1328250]

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PANX3	pannexin 3	Mapped by significant region
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region
PGR	progesterone receptor	Mapped by significant region	TAS[1557371]
FGF4	fibroblast growth factor 4	Mapped by significant region	TAS[2959959]
INS	insulin	Mapped by literature SNP	IC[7556975]
CCR5	chemokine (C-C motif) receptor 5	Mapped by PBA pathway	IDA[10679098]
CCL27	chemokine (C-C motif) ligand 27	Mapped by LD-proxy	TAS[10588729]
IHH	Indian hedgehog	Mapped by significant region
NR5A1	nuclear receptor subfamily 5, group A, member 1	Mapped by significant region	TAS[10369247]
CTF1	cardiotrophin 1	Mapped by CNV	TAS[7862649]
TRHDE	thyrotropin-releasing hormone degrading enzyme	Mapped by LD-proxy	TAS[10491199]
ADORA2A	adenosine A2a receptor	Mapped by CNV	TAS[7818494]
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	Mapped by CNV	TAS[9367155]
IL18	interleukin 18 (interferon-gamma-inducing factor)	Mapped by significant region	TAS[9792649]
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by significant region	TAS[7715640]
GJA8	gap junction protein, alpha 8, 50kDa	Mapped by CNV
BARX1	BARX homeobox 1	Mapped by significant region
GRAP	GRB2-related adaptor protein	Mapped by significant region	TAS[8647802]
INHA	inhibin, alpha	Mapped by significant region	TAS[12456957]
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	Mapped by significant region	TAS[10074428]
GJB2	gap junction protein, beta 2, 26kDa	Mapped by significant region
LHX1	LIM homeobox 1	Mapped by CNV
IL17C	interleukin 17C	Mapped by significant region	TAS[10639155]
FGF3	fibroblast growth factor 3	Mapped by significant region	TAS[2470007]
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	Mapped by significant region	TAS[8391931]
GJA3	gap junction protein, alpha 3, 46kDa	Mapped by significant region	TAS[9413992]
WNT6	wingless-type MMTV integration site family, member 6	Mapped by significant region
TXN	thioredoxin	Mapped by significant region	TAS[10947064]
FGF9	fibroblast growth factor 9 (glia-activating factor)	Mapped by significant region