ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GJB2
Previous Symbol	DFNB1, DFNA3
Symbol Alias	CX26, NSRD1
Approved Name	gap junction protein, beta 2, 26kDa
Previous Name	gap junction protein, beta 2, 26kD (connexin 26), "gap junction protein, beta 2, 26kDa (connexin 26)"
Name Alias	connexin 26
Location	13q11-q12
Position	chr13:20761602-20767114, -
External Links	HGNC: 4284 Entrez Gene: 2706 Ensembl: ENSG00000165474 UCSC: uc001umy.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
13q12.11	chr13:19500000-23300000	1 (1/0/0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Cellular Component		17
GO:0005243	gap junction channel activity	Molecular Function		3
GO:0007267	cell-cell signaling	Biological Process		38
GO:0006810	transport	Biological Process	TAS[1324944]	62
GO:0005922	connexon complex	Cellular Component		6
GO:0005886	plasma membrane	Cellular Component		772
GO:0016264	gap junction assembly	Biological Process		3
GO:0016044	cellular membrane organization	Biological Process		24
GO:0016021	integral to membrane	Cellular Component		845
GO:0007605	sensory perception of sound	Biological Process		31
GO:0030539	male genitalia development	Biological Process		4
GO:0016328	lateral plasma membrane	Cellular Component		8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GJB2 (count: 2)

Gene Symbol	Pathway Count	Pathway List
GJA1	7	gap junction channel activity; cell-cell signaling; transport; connexon complex; plasma membrane; gap junction assembly; cellular membrane organization;
GJA3	5	gap junction channel activity; cell-cell signaling; transport; connexon complex; integral to membrane;

Genes shared at least 2 KEGG pathways with GJB2 (count: 0)

View in gBrowse

Region: chr13:20761602..20767114 View in gBrowse