ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol ADRA2B
Previous Symbol ADRA2L1, ADRA2RL1
Symbol Alias ADRARL1
Approved Name adrenoceptor alpha 2B
Previous Name "adrenergic, alpha-2B-, receptor"
Location 2q11.1
Position chr2:96778707-96781984, -1
External Links HGNC: 282
Entrez Gene: 151
Ensembl: ENSG00000222040
UCSC: uc021vlh.1
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Hawi, Z., 2012 Although suggestive evidence of association (nominal p <= 0.05) with the genes SLC6A2, ADRA1A, ADRA1B and ADRA2B was observed, none remained significant after permutation adjustments. These findings provide evidence of a contribution of the noradrenaline system to the genetic aetiology of ADHD. Significant

Gene related SNPs (count: 8)

Literature-origin SNPs (count: 1)

LD-proxies (count: 7)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 21)


Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with ADRA2B (count: 14)

Genes shared at least 2 KEGG pathways with ADRA2B (count: 0)

View in gBrowse

Region: chr2:96778707..96781984 View in gBrowse
View in gBrowse