ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005578
Name proteinaceous extracellular matrix
Type cellular component
No. of Genes in ADHDgene  51
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 51)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MMP7 matrix metallopeptidase 7 (matrilysin, uterine) 11q21-q22 1(0/0/1) IEA
MMP24 matrix metallopeptidase 24 (membrane-inserted) 20q11.2 1(0/0/1) IEA
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 4q32.3 1(1/0/0) IEA
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) NAS[14570917]
GPC6 glypican 6 13q32 1(0/0/1) IEA
FLRT2 fibronectin leucine rich transmembrane protein 2 14q24-q32 1(0/1/0) NAS[10644439]
GPC5 glypican 5 13q32 1(0/0/1) IEA

Genes from other sources Help (count: 44)

Approved Symbol Approved Name Source Evidence[PMID]
MMP20 matrix metallopeptidase 20 Mapped by significant region IEA
ZG16 zymogen granule protein 16 Mapped by CNV IEA
MMP10 matrix metallopeptidase 10 (stromelysin 2) Mapped by significant region IEA
CHL1 cell adhesion molecule L1-like Mapped by CNV IEA
DGCR6 DiGeorge syndrome critical region gene 6 Mapped by CNV TAS[8733130]
COCH cochlin Mapped by significant region IEA
ECM2 extracellular matrix protein 2, female organ and adipocyte specific Mapped by significant region TAS[9790758]
MMP1 matrix metallopeptidase 1 (interstitial collagenase) Mapped by significant region IEA
NTN3 netrin 3 Mapped by significant region IEA
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 Mapped by LD-proxy IEA
MMP27 matrix metallopeptidase 27 Mapped by significant region IEA
MMP13 matrix metallopeptidase 13 (collagenase 3) Mapped by significant region IEA
WNT10A wingless-type MMTV integration site family, member 10A Mapped by significant region IEA
MMP11 matrix metallopeptidase 11 (stromelysin 3) Mapped by CNV IEA
MMP25 matrix metallopeptidase 25 Mapped by significant region NAS[10628838]
WNT6 wingless-type MMTV integration site family, member 6 Mapped by significant region IEA
CTGF connective tissue growth factor Mapped by significant region IEA
FLRT1 fibronectin leucine rich transmembrane protein 1 Mapped by significant region NAS[10644439]
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 Mapped by significant region IEA
MMP8 matrix metallopeptidase 8 (neutrophil collagenase) Mapped by significant region IEA
ZP2 zona pellucida glycoprotein 2 (sperm receptor) Mapped by significant region IEA
MMP12 matrix metallopeptidase 12 (macrophage elastase) Mapped by significant region IEA
MMP3 matrix metallopeptidase 3 (stromelysin 1, progelatinase) Mapped by significant region IEA
ZP4 zona pellucida glycoprotein 4 Mapped by CNV IEA
TNR tenascin R Mapped by significant region IEA
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 Mapped by significant region IEA
MMP16 matrix metallopeptidase 16 (membrane-inserted) Mapped by CNV IEA
OTOA otoancorin Mapped by significant region IEA
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 Mapped by significant region IEA
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 Mapped by CNV; Mapped by significant region IEA
LTBP1 latent transforming growth factor beta binding protein 1 Mapped by CNV NAS[8537398]
TNN tenascin N Mapped by significant region IEA
FN1 fibronectin 1 Mapped by significant region NAS
TECTA tectorin alpha Mapped by significant region IEA
HAPLN4 hyaluronan and proteoglycan link protein 4 Mapped by Literature SNP IEA
PRSS36 protease, serine, 36 Mapped by CNV IEA
OMD osteomodulin Mapped by significant region IEA
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 Mapped by Literature SNP; Mapped by CNV IEA
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 Mapped by significant region IEA
ZP1 zona pellucida glycoprotein 1 (sperm receptor) Mapped by significant region IEA
CD248 CD248 molecule, endosialin Mapped by significant region TAS[10947988]
OGN osteoglycin Mapped by significant region IEA
ASPN asporin Mapped by significant region IDA[17827158]
WNT11 wingless-type MMTV integration site family, member 11 Mapped by significant region IEA