ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GPC6
Approved Name	glypican 6
Name Alias	glypican proteoglycan 6
Location	13q32
Position	chr13:93879078-95060274, +
External Links	HGNC: 4454 Entrez Gene: 10082 Ensembl: ENSG00000183098 UCSC: uc001vlt.2
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lesch KP, 2008	Trend associated SNP was mapped in this gene.	Trend

Gene related SNPs (count: 16)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs7995215	Chr13:94408506(Fwd)	intron_variant	1(0/0/1)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0005975	carbohydrate metabolic process	Biological Process		50
GO:0005887	integral to plasma membrane	Cellular Component	TAS[10329016]	220
GO:0005886	plasma membrane	Cellular Component		772
GO:0005796	Golgi lumen	Cellular Component		12
GO:0005615	extracellular space	Cellular Component		126
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0043395	heparan sulfate proteoglycan binding	Molecular Function		3
GO:0043202	lysosomal lumen	Cellular Component		10
GO:0031225	anchored to membrane	Cellular Component		29
GO:0030204	chondroitin sulfate metabolic process	Biological Process		7
GO:0030203	glycosaminoglycan metabolic process	Biological Process		20
GO:0016477	cell migration	Biological Process		24
GO:0006027	glycosaminoglycan catabolic process	Biological Process		3
GO:0006024	glycosaminoglycan biosynthetic process	Biological Process		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GPC6 (count: 7)

Gene Symbol	Pathway Count	Pathway List
GPC5	14	small molecule metabolic process; carbohydrate metabolic process; integral to plasma membrane; plasma membrane; Golgi lumen; extracellular space; proteinaceous extracellular matrix; heparan sulfate proteoglycan binding; lysosomal lumen; anchored to membrane; chondroitin sulfate metabolic process; glycosaminoglycan metabolic process; glycosaminoglycan catabolic process; glycosaminoglycan biosynthetic process;
OGN	7	small molecule metabolic process; carbohydrate metabolic process; Golgi lumen; extracellular space; proteinaceous extracellular matrix; lysosomal lumen; glycosaminoglycan metabolic process;
OMD	6	small molecule metabolic process; carbohydrate metabolic process; Golgi lumen; proteinaceous extracellular matrix; lysosomal lumen; glycosaminoglycan metabolic process;
B3GAT3	5	small molecule metabolic process; carbohydrate metabolic process; chondroitin sulfate metabolic process; glycosaminoglycan metabolic process; glycosaminoglycan biosynthetic process;
CTGF	5	small molecule metabolic process; plasma membrane; extracellular space; proteinaceous extracellular matrix; cell migration;
HAS3	5	small molecule metabolic process; carbohydrate metabolic process; integral to plasma membrane; plasma membrane; glycosaminoglycan metabolic process;
STAB2	5	small molecule metabolic process; carbohydrate metabolic process; integral to plasma membrane; plasma membrane; glycosaminoglycan metabolic process;

Genes shared at least 2 KEGG pathways with GPC6 (count: 0)

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Region: chr13:93879078..95060274 View in gBrowse