ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ADAMTS7
Symbol Alias	ADAM-TS7, DKFZp434H204
Approved Name	ADAM metallopeptidase with thrombospondin type 1 motif, 7
Previous Name	a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7
Name Alias	COMPase, "a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein"
Location	15pter-qter
Position	chr15:79051545-79103773, -
External Links	HGNC: 223 Entrez Gene: 11173 Ensembl: ENSG00000136378 UCSC: uc002bej.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 4)

rs_ID	Location	Functional Annotation
rs11631955	Chr15:79085915(Fwd)	intron_variant; nc_transcript_variant
rs11630236	Chr15:79058298(Fwd)	downstream_gene_variant; missense_variant; upstream_gene_variant
rs7174367	Chr15:79064667(Fwd)	intron_variant; nc_transcript_variant
rs1809420	Chr15:79056769(Fwd)	downstream_gene_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006508	proteolysis	Biological Process		102
GO:0008237	metallopeptidase activity	Molecular Function	TAS[10464288]	13
GO:0004222	metalloendopeptidase activity	Molecular Function		33
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0008270	zinc ion binding	Molecular Function		323
GO:0009986	cell surface	Cellular Component		70

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ADAMTS7 (count: 4)

Gene Symbol	Pathway Count	Pathway List
ADAM8	5	proteolysis; metallopeptidase activity; metalloendopeptidase activity; zinc ion binding; cell surface;
ADAMTS2	5	proteolysis; metallopeptidase activity; metalloendopeptidase activity; proteinaceous extracellular matrix; zinc ion binding;
ADAMTS8	5	proteolysis; metallopeptidase activity; metalloendopeptidase activity; proteinaceous extracellular matrix; zinc ion binding;
MMP16	5	proteolysis; metalloendopeptidase activity; proteinaceous extracellular matrix; zinc ion binding; cell surface;

Genes shared at least 2 KEGG pathways with ADAMTS7 (count: 0)

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Region: chr15:79051545..79103773 View in gBrowse