ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ZP4
Symbol Alias	ZPB
Approved Name	zona pellucida glycoprotein 4
Location	1q43
Position	chr1:238041164-238054222, -
External Links	HGNC: 15770 Entrez Gene: 57829 Ensembl: ENSG00000116996 UCSC: uc001hym.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_45	chr1:235967993-237757467 (NCBI Build 36.1 (hg18))	1739833	1q43	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042102	positive regulation of T cell proliferation	Biological Process	IDA[19004505]	11
GO:0035556	intracellular signal transduction	Biological Process	IMP[18667750]	44
GO:0032190	acrosin binding	Molecular Function	IPI[15950651]	2
GO:0016021	integral to membrane	Cellular Component		845
GO:0010737	protein kinase A signaling cascade	Biological Process	IDA[18667750]	1
GO:0005886	plasma membrane	Cellular Component		772
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0004871	signal transducer activity	Molecular Function	IMP[18667750]	49
GO:2000360	negative regulation of binding of sperm to zona pellucida	Biological Process	IDA[18667750]	2
GO:2000344	positive regulation of acrosome reaction	Biological Process	IDA[18667750]	2
GO:0070528	protein kinase C signaling cascade	Biological Process	IMP[18667750]	1
GO:0060478	acrosomal vesicle exocytosis	Biological Process	IMP[19004505]	1
GO:0045860	positive regulation of protein kinase activity	Biological Process	IDA[18667750]	7
GO:0002922	positive regulation of humoral immune response	Biological Process	IDA[19004505]	1

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ZP4 (count: 0)

Genes shared at least 2 KEGG pathways with ZP4 (count: 0)

View in gBrowse

Region: chr1:238041164..238054222 View in gBrowse