ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0019904
Name protein domain specific binding
Type molecular function
No. of Genes in ADHDgene  43
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 43)

Literature-origin genes (count: 9)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IEA
STX1A syntaxin 1A (brain) 7q11.2 3(2/1/0) IEA
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0) IPI[17237226]
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
HOXB1 homeobox B1 17q21.32 1(0/0/1) IPI[10052460]
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 6(5/1/0) IEA
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IEA
XPO1 exportin 1 2p15 1(0/0/1) IEA

Genes from other sources Help (count: 34)

Approved Symbol Approved Name Source Evidence[PMID]
CHMP1A charged multivesicular body protein 1A Mapped by significant region IPI[17928862]
XPA xeroderma pigmentosum, complementation group A Mapped by significant region IPI[17720715]
PHRF1 PHD and ring finger domains 1 Mapped by LD-proxy IEA
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region TAS[18421703]
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy IEA
TJP1 tight junction protein 1 Mapped by CNV; Mapped by significant region IEA
MYO7A myosin VIIA Mapped by significant region IEA
NDE1 nudE neurodevelopment protein 1 Mapped by CNV; Mapped by significant region IEA
CTNND1 catenin (cadherin-associated protein), delta 1 Mapped by significant region IEA
BASP1 brain abundant, membrane attached signal protein 1 Mapped by significant region IPI[14701728]
KCTD13 potassium channel tetramerization domain containing 13 Mapped by CNV IEA
CBX3 chromobox homolog 3 Mapped by CNV; Mapped by significant region IPI[9636147]
ESRRA estrogen-related receptor alpha Mapped by significant region IPI[11984006]
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IPI[12447383]
ARFIP2 ADP-ribosylation factor interacting protein 2 Mapped by CNV IEA
MED12 mediator complex subunit 12 Mapped by PBA pathway IPI[11984006]
CHMP1B charged multivesicular body protein 1B Mapped by Literature SNP IPI[17928862]
FAM92B family with sequence similarity 92, member B Mapped by significant region IEA
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 Mapped by significant region IEA
RAB27B RAB27B, member RAS oncogene family Mapped by Literature SNP IPI[16880209]
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) Mapped by significant region IPI[12411443]
AKAP7 A kinase (PRKA) anchor protein 7 Mapped by significant region IEA
STX1B syntaxin 1B Mapped by CNV IEA
TACC2 transforming, acidic coiled-coil containing protein 2 Mapped by PBA pathway IEA
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 Mapped by CNV; Mapped by significant region IPI[10947987]
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV IEA
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta Mapped by significant region IEA
ZNF521 zinc finger protein 521 Mapped by significant region IPI[11984006]
NCK1 NCK adaptor protein 1 Mapped by PBA pathway IEA
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta Mapped by PBA pathway ISS
PICK1 protein interacting with PRKCA 1 Mapped by Literature SNP IEA
MRPL17 mitochondrial ribosomal protein L17 Mapped by CNV IPI[11984006]
PKD1 polycystic kidney disease 1 (autosomal dominant) Mapped by significant region IPI[9171830]
CENPJ centromere protein J Mapped by PBA pathway IPI[11984006]