ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006357
Name regulation of transcription from RNA polymerase II promoter
Type biological process
No. of Genes in ADHDgene  46
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 46)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1) TAS[7660129]
MED27 mediator complex subunit 27 9q34.13 1(0/1/0) IDA[9989412]
HES6 hes family bHLH transcription factor 6 2q37.3 1(0/1/0) IEA
CLOCK clock circadian regulator 4q12 2(2/0/0) TAS[10198158]
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IMP[18093989]
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 1(0/0/1) TAS[9787080]

Genes from other sources Help (count: 40)

Approved Symbol Approved Name Source Evidence[PMID]
UTF1 undifferentiated embryonic cell transcription factor 1 Mapped by CNV TAS[9748258]
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 Mapped by significant region IMP[18974355]
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 Mapped by significant region IEA
NRF1 nuclear respiratory factor 1 Mapped by LD-proxy TAS[8034649]
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 Mapped by PBA pathway IMP[17363140]; NAS[8804307]
POU2F3 POU class 2 homeobox 3 Mapped by significant region TAS[10473598]
LITAF lipopolysaccharide-induced TNF factor Mapped by significant region TAS[10200294]
SOX30 SRY (sex determining region Y)-box 30 Mapped by significant region IDA[10359848]; IDA[10359848]
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa Mapped by significant region TAS[9674425]
SP4 Sp4 transcription factor Mapped by significant region IDA[12560508]
MED16 mediator complex subunit 16 Mapped by PBA pathway NAS[10198638]
SNW1 SNW domain containing 1 Mapped by PBA pathway TAS[9632709]
ATF6 activating transcription factor 6 Mapped by CNV TAS[10564271]
SRCAP Snf2-related CREBBP activator protein Mapped by CNV TAS[10347196]
MED20 mediator complex subunit 20 Mapped by CNV TAS[9933582]
FOSL1 FOS-like antigen 1 Mapped by significant region TAS[10918580]
NEUROD2 neuronal differentiation 2 Mapped by LD-proxy TAS[8816493]
MED14 mediator complex subunit 14 Mapped by PBA pathway TAS[9989412]
CIAO1 cytosolic iron-sulfur assembly component 1 Mapped by LD-proxy TAS[9556563]
GSC2 goosecoid homeobox 2 Mapped by CNV IDA[9700206]
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 Mapped by significant region IDA[12721286]
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV NAS[8804307]
SUB1 SUB1 homolog (S. cerevisiae) Mapped by significant region IDA[8062391]
ZNF367 zinc finger protein 367 Mapped by significant region IDA[15344908]
UBN1 ubinuclein 1 Mapped by significant region TAS[10725330]
DEAF1 DEAF1 transcription factor Mapped by Literature SNP IEA
KDM1A lysine (K)-specific demethylase 1A Mapped by LD-proxy IMP[16079795]
MED23 mediator complex subunit 23 Mapped by significant region TAS[9989412]
RBBP8 retinoblastoma binding protein 8 Mapped by significant region TAS[10764811]
SAP18 Sin3A-associated protein, 18kDa Mapped by significant region TAS[9150135]
RAI1 retinoic acid induced 1 Mapped by significant region IEA
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region IDA[11818576]; TAS[11714725]
MED7 mediator complex subunit 7 Mapped by significant region IDA[9989412]
MED17 mediator complex subunit 17 Mapped by significant region; Mapped by PBA pathway IDA[9989412]
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region TAS[8156598]
PKNOX2 PBX/knotted 1 homeobox 2 Mapped by significant region IEA
TBX1 T-box 1 Mapped by CNV ISS; NAS[9268629]
TBX10 T-box 10 Mapped by significant region TAS[9545502]
ELP2 elongator acetyltransferase complex subunit 2 Mapped by significant region TAS[11714725]
HIRA histone cell cycle regulator Mapped by CNV TAS[9731536]