ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045211
Name postsynaptic membrane
Type cellular component
No. of Genes in ADHDgene  45
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 45)

Literature-origin genes (count: 17)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0) IEA
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2(0/2/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) IEA
GRIK4 glutamate receptor, ionotropic, kainate 4 11q23.3 1(0/1/0) IEA
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 11q23.1 3(1/2/0) IEA
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 2(1/1/0) IEA
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1) IEA
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) IEA
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 1(0/0/1) IEA
FAIM2 Fas apoptotic inhibitory molecule 2 12q13 1(0/1/0) IEA
DISC1 disrupted in schizophrenia 1 1q42.1 1(1/0/0) IEA
GRM7 glutamate receptor, metabotropic 7 3p26-p25 3(2/1/0) ISS
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 11q23.1-q23.2 1(0/1/0) IEA
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 4(1/3/0) IEA
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 15q13.3 2(0/1/1) IEA

Genes from other sources Help (count: 28)

Approved Symbol Approved Name Source Evidence[PMID]
GOPC golgi-associated PDZ and coiled-coil motif containing Mapped by significant region IEA
NLGN1 neuroligin 1 Mapped by CNV IEA
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) Mapped by LD-proxy IEA
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 Mapped by significant region ISS
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion Mapped by significant region IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Mapped by CNV; Mapped by significant region IEA
DLG2 discs, large homolog 2 (Drosophila) Mapped by significant region IEA
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region IEA
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IEA
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway IEA
GRIA4 glutamate receptor, ionotropic, AMPA 4 Mapped by significant region IEA
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) Mapped by LD-proxy IEA
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region ISS
CNIH2 cornichon family AMPA receptor auxiliary protein 2 Mapped by significant region ISS
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region ISS
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway ISS
RAPSN receptor-associated protein of the synapse Mapped by LD-proxy IEA
MUSK muscle, skeletal, receptor tyrosine kinase Mapped by significant region ISS
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region IEA
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 Mapped by PBA pathway IEA
CHRM5 cholinergic receptor, muscarinic 5 Mapped by CNV; Mapped by PBA pathway IEA
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway IEA
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IBA
CLSTN2 calsyntenin 2 Mapped by CNV IEA
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Mapped by CNV; Mapped by significant region IEA
PSD3 pleckstrin and Sec7 domain containing 3 Mapped by Literature SNP IEA
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Mapped by significant region IEA