ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006954
Name inflammatory response
Type Biological Process
No. of Genes in ADHDgene  51
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 51)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0)
BMPR1B bone morphogenetic protein receptor, type IB 4q23-q24 1(0/0/1)
MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 1(0/1/0)
CAMK1D calcium/calmodulin-dependent protein kinase ID 10p13 1(0/0/1)

Genes from other sources Help (count: 47)

Approved Symbol Approved Name Source Evidence[PMID]
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IDA[10443688]
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 Mapped by significant region
CCR5 chemokine (C-C motif) receptor 5 Mapped by PBA pathway TAS[8639485]
NOX4 NADPH oxidase 4 Mapped by significant region TAS[10869423]
ADAM8 ADAM metallopeptidase domain 8 Mapped by CNV; Mapped by LD-proxy IDA[17548643]
PRDX5 peroxiredoxin 5 Mapped by significant region TAS[10521424]
CYBA cytochrome b-245, alpha polypeptide Mapped by significant region IMP[2243141]
IL18 interleukin 18 (interferon-gamma-inducing factor) Mapped by significant region
APOL3 apolipoprotein L, 3 Mapped by CNV TAS[10233894]
MGLL monoglyceride lipase Mapped by PBA pathway TAS[9495531]
PLA2G2E phospholipase A2, group IIE Mapped by PBA pathway TAS[10681567]
VNN1 vanin 1 Mapped by significant region ISS[15282320]
C5 complement component 5 Mapped by significant region TAS[8759757]
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) Mapped by CNV NAS[8103515]
PYCARD PYD and CARD domain containing Mapped by CNV
S1PR3 sphingosine-1-phosphate receptor 3 Mapped by significant region
ORM1 orosomucoid 1 Mapped by significant region TAS[3360326]
PLA2G2D phospholipase A2, group IID Mapped by PBA pathway TAS[10455175]
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region TAS[9725262]
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region TAS[1777480]
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) Mapped by PBA pathway; Mapped by significant region
ADORA2A adenosine A2a receptor Mapped by CNV TAS[8360491]
PRKD1 protein kinase D1 Mapped by significant region
GAL galanin prepropeptide Mapped by CNV; Mapped by significant region
CCL19 chemokine (C-C motif) ligand 19 Mapped by LD-proxy NAS[14592837]
C3AR1 complement component 3a receptor 1 Mapped by PBA pathway TAS[8765043]
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mapped by significant region IDA[12924514]
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 Mapped by significant region
ATRN attractin Mapped by CNV
APOC3 apolipoprotein C-III Mapped by significant region
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide Mapped by CNV TAS[17290298]
AOAH acyloxyacyl hydrolase (neutrophil) Mapped by PBA pathway TAS[1883828]
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin Mapped by CNV NAS[11133773]
BDKRB2 bradykinin receptor B2 Mapped by PBA pathway IC[17077303]
CARD18 caspase recruitment domain family, member 18 Mapped by significant region NAS[11051551]
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mapped by CNV
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein Mapped by significant region
CXCR1 chemokine (C-X-C motif) receptor 1 Mapped by significant region TAS[10725748]
IL17D interleukin 17D Mapped by significant region
IL17C interleukin 17C Mapped by significant region
PLA2G4B phospholipase A2, group IVB (cytosolic) Mapped by PBA pathway NAS[10085124]
GGT5 gamma-glutamyltransferase 5 Mapped by CNV
LTB4R leukotriene B4 receptor Mapped by significant region
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) Mapped by PBA pathway NAS[10085124]
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 Mapped by significant region TAS[7749981]
MEP1B meprin A, beta Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014