ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GGT5
Previous Symbol	GGTLA1
Symbol Alias	GGT-REL
Approved Name	gamma-glutamyltransferase 5
Previous Name	"gamma-glutamyltransferase-like activity 1"
Location	22q11.23
Position	chr22:24615622-24641110, -1
External Links	HGNC: 4260 Entrez Gene: 2687 Ensembl: ENSG00000099998 UCSC: uc002zzp.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_37	chr22:22020325-23326630 (NCBI Build 36.1 (hg18))	1306306	22q11.23	Gain

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019370	leukotriene biosynthetic process	biological process	ISS	10
GO:0005886	plasma membrane	cellular component	TAS	839
GO:0031362	anchored to external side of plasma membrane	cellular component	TAS[18357469]	5
GO:0006954	inflammatory response	biological process	IEA	54
GO:0006750	glutathione biosynthetic process	biological process	IEA	6
GO:0003840	gamma-glutamyltransferase activity	molecular function	TAS[18357469]	4
GO:0006749	glutathione metabolic process	biological process	TAS[18357469]	7
GO:0006520	cellular amino acid metabolic process	biological process	TAS[1676842]	8
GO:0016787	hydrolase activity	molecular function	IEA	16
GO:0016021	integral to membrane	cellular component	IEA	932

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GGT5 (count: 2)

Gene Symbol	Pathway Count	Pathway List
GGT1	9	leukotriene biosynthetic process; plasma membrane; anchored to external side of plasma membrane; glutathione biosynthetic process; gamma-glutamyltransferase activity; glutathione metabolic process; cellular amino acid metabolic process; hydrolase activity; integral to membrane;
GGTA1P	5	leukotriene biosynthetic process; anchored to external side of plasma membrane; gamma-glutamyltransferase activity; glutathione metabolic process; integral to membrane;

Genes shared at least 2 KEGG pathways with GGT5 (count: 0)

View in gBrowse

Region: chr22:24615622..24641110 View in gBrowse