ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005543
Name phospholipid binding
Type molecular function
No. of Genes in ADHDgene  66
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 66)

Literature-origin genes (count: 14)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
PRKD1 protein kinase D1 14q11 1(0/1/0) IEA
SH2B1 SH2B adaptor protein 1 16p11.2 1(0/1/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) TAS[1840599]
NET1 neuroepithelial cell transforming 1 10p15 1(1/0/0) IEA
PHLDA1 pleckstrin homology-like domain, family A, member 1 12q15 1(0/1/0) IEA
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) IEA
DNM1 dynamin 1 9q34 1(0/0/1) IEA
DGKH diacylglycerol kinase, eta 13q13.3 2(1/1/0) IEA
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1) IEA
TRIO trio Rho guanine nucleotide exchange factor 5p14-p15.1 1(0/0/1) IEA
ADRBK2 adrenergic, beta, receptor kinase 2 22q11 1(0/1/0) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IEA
DOCK10 dedicator of cytokinesis 10 2q36.3 1(0/0/1) IEA
PLCL1 phospholipase C-like 1 2q33 1(0/0/1) IEA

Genes from other sources Help (count: 52)

Approved Symbol Approved Name Source Evidence[PMID]
RASA1 RAS p21 protein activator (GTPase activating protein) 1 Mapped by PBA pathway IEA
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 Mapped by CNV; Mapped by significant region IC[16702602]
SPTBN2 spectrin, beta, non-erythrocytic 2 Mapped by significant region IEA
BAD BCL2-associated agonist of cell death Mapped by significant region IMP
DAB2IP DAB2 interacting protein Mapped by significant region IEA
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B Mapped by significant region IEA
STAP1 signal transducing adaptor family member 1 Mapped by significant region IEA
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway IEA
SYNGAP1 synaptic Ras GTPase activating protein 1 Mapped by Literature SNP IEA
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 Mapped by significant region IEA
OSBPL3 oxysterol binding protein-like 3 Mapped by CNV; Mapped by significant region IEA
RTKN2 rhotekin 2 Mapped by CNV IEA
SPATA13 spermatogenesis associated 13 Mapped by Literature SNP; Mapped by CNV IEA
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 Mapped by CNV; Mapped by significant region IEA
NOXO1 NADPH oxidase organizer 1 Mapped by significant region TAS[16636067]
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 Mapped by CNV; Mapped by significant region IEA
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) Mapped by significant region IEA
NR5A1 nuclear receptor subfamily 5, group A, member 1 Mapped by significant region IDA[17664281]
F10 coagulation factor X Mapped by CNV IDA[17469850]
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) Mapped by PBA pathway NAS[10085124]
GRB10 growth factor receptor-bound protein 10 Mapped by LD-proxy IEA
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 Mapped by CNV IEA
OSBP oxysterol binding protein Mapped by significant region IEA
FGD3 FYVE, RhoGEF and PH domain containing 3 Mapped by significant region IEA
ARHGAP20 Rho GTPase activating protein 20 Mapped by significant region IEA
APOA5 apolipoprotein A-V Mapped by significant region IDA[12810715]
LPAR1 lysophosphatidic acid receptor 1 Mapped by significant region IEA
PLCD4 phospholipase C, delta 4 Mapped by significant region IEA
SKAP2 src kinase associated phosphoprotein 2 Mapped by significant region IEA
ARHGAP42 Rho GTPase activating protein 42 Mapped by significant region IEA
PLCH1 phospholipase C, eta 1 Mapped by PBA pathway IEA
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 Mapped by significant region IEA
PSD3 pleckstrin and Sec7 domain containing 3 Mapped by Literature SNP IEA
SH2B3 SH2B adaptor protein 3 Mapped by LD-proxy IEA
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 Mapped by significant region IEA
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) Mapped by PBA pathway IDA[9032461]
FERMT3 fermitin family member 3 Mapped by significant region IEA
CMIP c-Maf inducing protein Mapped by significant region IEA
MPRIP myosin phosphatase Rho interacting protein Mapped by significant region IEA
OSBPL1A oxysterol binding protein-like 1A Mapped by significant region NAS[11279184]
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Mapped by LD-proxy IEA
TBC1D2 TBC1 domain family, member 2 Mapped by significant region IEA
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region IEA
PLCD1 phospholipase C, delta 1 Mapped by PBA pathway IEA
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 Mapped by CNV; Mapped by significant region IEA
SNTG2 syntrophin, gamma 2 Mapped by CNV IEA
PHLDB1 pleckstrin homology-like domain, family B, member 1 Mapped by significant region IEA
ITK IL2-inducible T-cell kinase Mapped by significant region IEA
APOA1 apolipoprotein A-I Mapped by significant region IDA[12810715]
APOC3 apolipoprotein C-III Mapped by significant region IDA[11060345]
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 Mapped by significant region IEA
DOK6 docking protein 6 Mapped by CNV IEA