ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0043065
Name	positive regulation of apoptotic process
Type	Biological Process
No. of Genes in ADHDgene	34
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 34)

Literature-origin genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DUSP1	dual specificity phosphatase 1	5q35.1	1(0/1/0)
NET1	neuroepithelial cell transforming 1	10p15	0
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	16p13.2	3(1/2/0)
CNR1	cannabinoid receptor 1 (brain)	6q14-q15	1(1/0/0)

Genes from other sources (count: 30)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PYCARD	PYD and CARD domain containing	Mapped by CNV	IDA[12646168]
APC	adenomatous polyposis coli	Mapped by LD-proxy; Mapped by PBA pathway	IMP[17227893]
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	Mapped by significant region
FLCN	folliculin	Mapped by significant region
ATM	ataxia telangiectasia mutated	Mapped by CNV; Mapped by significant region	IMP[17875758]
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	Mapped by CNV; Mapped by PBA pathway
ZBTB16	zinc finger and BTB domain containing 16	Mapped by significant region
MEN1	multiple endocrine neoplasia I	Mapped by significant region
WWOX	WW domain containing oxidoreductase	Mapped by significant region
DCUN1D3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)	Mapped by significant region	IMP[18823379]
WNT11	wingless-type MMTV integration site family, member 11	Mapped by significant region
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	Mapped by CNV	IDA[18468999]
PDIA3	protein disulfide isomerase family A, member 3	Mapped by PBA pathway
NOX4	NADPH oxidase 4	Mapped by significant region
DAB2IP	DAB2 interacting protein	Mapped by significant region	IDA[12813029]
KLF11	Kruppel-like factor 11	Mapped by significant region
FADD	Fas (TNFRSF6)-associated via death domain	Mapped by significant region
MAPK9	mitogen-activated protein kinase 9	Mapped by CNV
BCLAF1	BCL2-associated transcription factor 1	Mapped by significant region	IDA[10330179]
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region
HOXA5	homeobox A5	Mapped by significant region	IDA[10879542]
FOSL1	FOS-like antigen 1	Mapped by significant region
BARD1	BRCA1 associated RING domain 1	Mapped by significant region	IMP[15782130]
MAP3K5	mitogen-activated protein kinase kinase kinase 5	Mapped by LD-proxy; Mapped by significant region
GAL	galanin prepropeptide	Mapped by CNV; Mapped by significant region
HOXA13	homeobox A13	Mapped by significant region
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	Mapped by significant region
LPAR1	lysophosphatidic acid receptor 1	Mapped by significant region
RAD9A	RAD9 homolog A (S. pombe)	Mapped by significant region
BAD	BCL2-associated agonist of cell death	Mapped by significant region	IDA[9388232]; IMP[17289999]