ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005525
Name GTP binding
Type Molecular Function
No. of Genes in ADHDgene  53
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 53)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1p13 1(1/0/0) NAS[1936270]
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0)
DIRAS2 DIRAS family, GTP-binding RAS-like 2 9q22.32 1(1/0/0)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0)
DNM1 dynamin 1 9q34 1(0/0/1)

Genes from other sources Help (count: 47)

Approved Symbol Approved Name Source Evidence[PMID]
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy
RHOD ras homolog gene family, member D Mapped by significant region
TUBA3D tubulin, alpha 3d Mapped by CNV; Mapped by significant region
RAB1B RAB1B, member RAS oncogene family Mapped by significant region
GVINP1 GTPase, very large interferon inducible pseudogene 1 Mapped by CNV
TUBA4A tubulin, alpha 4a Mapped by significant region
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 Mapped by significant region
TUBA3E tubulin, alpha 3e Mapped by significant region
RAB2A RAB2A, member RAS oncogene family Mapped by PBA pathway IDA[16034420]
ACSM5 acyl-CoA synthetase medium-chain family member 5 Mapped by significant region
TUBA4B tubulin, alpha 4b (pseudogene) Mapped by significant region
ARL17B ADP-ribosylation factor-like 17B Mapped by LD-proxy
SEPT5 septin 5 Mapped by CNV
GMPPA GDP-mannose pyrophosphorylase A Mapped by significant region
ATL3 atlastin GTPase 3 Mapped by significant region
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Mapped by significant region
RAB27B RAB27B, member RAS oncogene family Mapped by LD-proxy; Mapped by literature SNP
ARL2 ADP-ribosylation factor-like 2 Mapped by significant region IMP[10831612]
RAN RAN, member RAS oncogene family Mapped by PBA pathway IDA[1961752]
EHD3 EH-domain containing 3 Mapped by CNV
TUBG1 tubulin, gamma 1 Mapped by PBA pathway
SCG5 secretogranin V (7B2 protein) Mapped by CNV; Mapped by significant region TAS[3134253]
RASL11B RAS-like, family 11, member B Mapped by CNV
SEPT1 septin 1 Mapped by CNV
HBS1L HBS1-like (S. cerevisiae) Mapped by significant region
DRG2 developmentally regulated GTP binding protein 2 Mapped by significant region
RIT2 Ras-like without CAAX 2 Mapped by significant region
TUBB3 tubulin, beta 3 Mapped by significant region
EHD1 EH-domain containing 1 Mapped by significant region
ARHGAP5 Rho GTPase activating protein 5 Mapped by significant region
RAB30 RAB30, member RAS oncogene family Mapped by significant region
DIRAS1 DIRAS family, GTP-binding RAS-like 1 Mapped by LD-proxy
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway TAS[10913182]
RAB38 RAB38, member RAS oncogene family Mapped by significant region NAS[10910072]
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Mapped by LD-proxy
RASD1 RAS, dexamethasone-induced 1 Mapped by significant region
RNF112 ring finger protein 112 Mapped by significant region
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa Mapped by CNV
ACSM1 acyl-CoA synthetase medium-chain family member 1 Mapped by significant region
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IDA[19141279]
MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae) Mapped by CNV
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV
RAB14 RAB14, member RAS oncogene family Mapped by PBA pathway; Mapped by significant region IDA[16034420]
SRPR signal recognition particle receptor (docking protein) Mapped by significant region
RAB6C RAB6C, member RAS oncogene family Mapped by significant region
ARFIP2 ADP-ribosylation factor interacting protein 2 Mapped by CNV TAS[8670882]

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014