ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007626
Name locomotory behavior
Type biological process
No. of Genes in ADHDgene  26
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 14)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DRD3 dopamine receptor D3 3q13.3 8(1/7/0) ISS
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) IEA
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0) IEA
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IEA
NPAS3 neuronal PAS domain protein 3 14q13.1 1(1/0/0) IEA
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) IEA
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0) IEA
ADRA1B adrenoceptor alpha 1B 5q33.3 2(1/1/0) IEA
GRM5 glutamate receptor, metabotropic 5 11q14.3 2(1/0/1) IEA
DRD2 dopamine receptor D2 11q22-q23 10(3/7/0) ISS
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0) IEA
TH tyrosine hydroxylase 11p15.5 7(2/5/0) ISS
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24 1(0/1/0) ISS

Genes from other sources Help (count: 12)

Approved Symbol Approved Name Source Evidence[PMID]
ANKH ANKH inorganic pyrophosphate transport regulator Mapped by significant region NAS[10894769]
ABAT 4-aminobutyrate aminotransferase Mapped by significant region IEA
GRM6 glutamate receptor, metabotropic 6 Mapped by CNV IEA
SEPP1 selenoprotein P, plasma, 1 Mapped by CNV; Mapped by significant region IEA
MYO15A myosin XVA Mapped by significant region IEA
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit Mapped by significant region; Mapped by PBA pathway IEA
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 Mapped by CNV; Mapped by significant region IEA
APLP2 amyloid beta (A4) precursor-like protein 2 Mapped by significant region IEA
ADORA2A adenosine A2a receptor Mapped by CNV IEA
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) Mapped by LD-proxy IEA
NOVA1 neuro-oncological ventral antigen 1 Mapped by significant region TAS[8558240]
BSX brain-specific homeobox Mapped by significant region IEA