ADHDgene Database

Gene Report

Basic Info

Approved Symbol	APBA2
Previous Symbol	X11L, MINT2
Symbol Alias	D15S1518E, LIN-10, MGC:14091, HsT16821
Approved Name	amyloid beta (A4) precursor protein-binding, family A, member 2
Previous Name	X11-like, "amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like)"
Location	15q11-q12
Position	chr15:29213840-29447484, +
External Links	HGNC: 579 Entrez Gene: 321 Ensembl: ENSG00000034053 UCSC: uc001zck.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 3)

ID	Location	Size	Band	Type
CNV_Williams[2010]_51	chr15:27000239-28153539 (NCBI Build 36.1 (hg18))	1153301	15q13.1-15q13.2	Gain
CNV_Williams[2010]_47	chr15:27013177-28153539 (NCBI Build 36.1 (hg18))	1140363	15q13.1-15q13.2	Gain
CNV_Jarick[2012]_29	chr15:27216380-28153539 (NCBI36 / hg18)	937160	15q13.1-15q13.2	dup

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
15q11.2-13.3	chr15:20700000-33600000	1 (1/0/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007399	nervous system development	Biological Process	TAS[9890987]	54
GO:0007268	synaptic transmission	Biological Process		96
GO:0010468	regulation of gene expression	Biological Process		7
GO:0007626	locomotory behavior	Biological Process		24
GO:0035264	multicellular organism growth	Biological Process		10
GO:0015031	protein transport	Biological Process		75
GO:0001701	in utero embryonic development	Biological Process		32
GO:0001540	beta-amyloid binding	Molecular Function		6
GO:0005886	plasma membrane	Cellular Component		772
GO:0005515	protein binding	Molecular Function	IPI[10833507]	910

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with APBA2 (count: 1)

Gene Symbol	Pathway Count	Pathway List
ACHE	5	nervous system development; synaptic transmission; beta-amyloid binding; plasma membrane; protein binding;

Genes shared at least 2 KEGG pathways with APBA2 (count: 0)

View in gBrowse

Region: chr15:29213840..29447484 View in gBrowse