ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006955
Name immune response
Type Biological Process
No. of Genes in ADHDgene  45
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 45)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
IL1RN interleukin 1 receptor antagonist 2q14.2 2(1/1/0) NAS[7629520]
NFIL3 nuclear factor, interleukin 3 regulated 9q22 2(1/1/0) TAS[7565758]
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 6p21.3 2(1/1/0)
IL16 interleukin 16 (lymphocyte chemoattractant factor) 15q26.3 1(0/0/1) TAS[9144227]

Genes from other sources Help (count: 41)

Approved Symbol Approved Name Source Evidence[PMID]
CCL27 chemokine (C-C motif) ligand 27 Mapped by LD-proxy
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) Mapped by CNV TAS[2139735]
CXCL12 chemokine (C-X-C motif) ligand 12 Mapped by PBA pathway
SPN sialophorin Mapped by CNV TAS[2023632]
CTSG cathepsin G Mapped by significant region TAS[2569462]
SUSD2 sushi domain containing 2 Mapped by CNV
IRF8 interferon regulatory factor 8 Mapped by significant region TAS[8861914]
CCR5 chemokine (C-C motif) receptor 5 Mapped by PBA pathway TAS[8639485]
FTH1 ferritin, heavy polypeptide 1 Mapped by significant region
PRG3 proteoglycan 3 Mapped by significant region
IGSF6 immunoglobulin superfamily, member 6 Mapped by significant region TAS[9809579]
IL18 interleukin 18 (interferon-gamma-inducing factor) Mapped by significant region TAS[8999896]
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) Mapped by significant region
IL7R interleukin 7 receptor Mapped by significant region TAS[9843216]
IGLL1 immunoglobulin lambda-like polypeptide 1 Mapped by CNV NAS[2501791]
IGHV1OR15-1 immunoglobulin heavy variable 1/OR15-1 (pseudogene) Mapped by significant region NAS[2841108]
ETS1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) Mapped by significant region TAS[2187191]
PTGER4 prostaglandin E receptor 4 (subtype EP4) Mapped by significant region IEP[8862514]
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 Mapped by significant region TAS[7515885]
MR1 major histocompatibility complex, class I-related Mapped by significant region
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) Mapped by significant region NAS[10932188]
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Mapped by CNV TAS[2138330]
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 Mapped by significant region TAS[7920628]
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) Mapped by CNV NAS[2531080]
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 Mapped by CNV TAS[2247090]
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 Mapped by significant region
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 Mapped by significant region
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 Mapped by significant region
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region TAS[9751059]
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Mapped by significant region TAS[8876214]
TAPBP TAP binding protein (tapasin) Mapped by LD-proxy TAS[9271576]
LTB4R leukotriene B4 receptor Mapped by significant region TAS[9177352]
FYB FYN binding protein Mapped by significant region TAS[9207119]
CTSC cathepsin C Mapped by significant region TAS[9092576]
TRIM22 tripartite motif containing 22 Mapped by CNV TAS[7797467]
TLR4 toll-like receptor 4 Mapped by significant region TAS[10426995]
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) Mapped by CNV TAS[2142460]
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 Mapped by significant region
CCL19 chemokine (C-C motif) ligand 19 Mapped by LD-proxy
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle Mapped by CNV
CTSW cathepsin W Mapped by significant region TAS[9823953]