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- Data Summary
GO Report
Basic Info
| ID | GO:0034641 |
|---|---|
| Name | cellular nitrogen compound metabolic process |
| Type | Biological Process |
| No. of Genes in ADHDgene | 30 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 30)
Literature-origin genes (count: 10)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 7p11 | 6(5/1/0) | |
| PNMT | phenylethanolamine N-methyltransferase | 17q | 3(2/1/0) | |
| TPH2 | tryptophan hydroxylase 2 | 12q15 | 10(7/3/0) | |
| TH | tyrosine hydroxylase | 11p15.5 | 7(2/5/0) | |
| AANAT | aralkylamine N-acetyltransferase | 17q25 | 1(0/0/1) | |
| TDO2 | tryptophan 2,3-dioxygenase | 4q31-q32 | 1(1/0/0) | |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 11p11.2 | 1(0/0/1) | |
| TPH1 | tryptophan hydroxylase 1 | 11p15.3-p14 | 6(2/4/0) | |
| DBH | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 9q34 | 20(11/9/0) | |
| ASMT | acetylserotonin O-methyltransferase | Xp22.3 and Yp11.3 | 1(1/0/0) |
Genes from other sources (count: 20)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| AUH | AU RNA binding protein/enoyl-CoA hydratase | Mapped by significant region | |
| ACAT1 | acetyl-CoA acetyltransferase 1 | Mapped by CNV; Mapped by significant region | |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | Mapped by significant region | |
| AGXT2 | alanine--glyoxylate aminotransferase 2 | Mapped by significant region | |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | Mapped by significant region | |
| ODC1 | ornithine decarboxylase 1 | Mapped by significant region | |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | Mapped by significant region | |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase | Mapped by LD-proxy | |
| ARG1 | arginase, liver | Mapped by significant region | |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | Mapped by significant region | |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 | Mapped by CNV; Mapped by significant region | |
| PAOX | polyamine oxidase (exo-N4-amino) | Mapped by CNV | |
| PRODH | proline dehydrogenase (oxidase) 1 | Mapped by CNV | |
| GLUL | glutamate-ammonia ligase | Mapped by significant region | |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | Mapped by significant region | |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | Mapped by significant region | |
| PSMA8 | proteasome (prosome, macropain) subunit, alpha type, 8 | Mapped by significant region | |
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | Mapped by significant region | |
| IYD | iodotyrosine deiodinase | Mapped by CNV | |
| CKMT1A | creatine kinase, mitochondrial 1A | Mapped by LD-proxy |