ADHDgene Database

Gene Report

Basic Info

Approved Symbol	HIBADH
Symbol Alias	NS5ATP1
Approved Name	3-hydroxyisobutyrate dehydrogenase
Location	7p15
Position	chr7:27565059-27702620, -
External Links	HGNC: 4907 Entrez Gene: 11112 Ensembl: ENSG00000106049 UCSC: uc003szf.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0051287	NAD binding	Molecular Function		4
GO:0009083	branched-chain amino acid catabolic process	Biological Process		5
GO:0034641	cellular nitrogen compound metabolic process	Biological Process		30
GO:0006574	valine catabolic process	Biological Process	IDA[16466957]	2
GO:0008442	3-hydroxyisobutyrate dehydrogenase activity	Molecular Function	IDA[16466957]	1
GO:0005759	mitochondrial matrix	Cellular Component		32
GO:0006098	pentose-phosphate shunt	Biological Process		1
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	Molecular Function		1
GO:0005739	mitochondrion	Cellular Component		183

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00280	Valine, leucine and isoleucine degradation	7

Genes shared at least 5 GO terms with HIBADH (count: 3)

Gene Symbol	Pathway Count	Pathway List
ACAD8	5	small molecule metabolic process; branched-chain amino acid catabolic process; cellular nitrogen compound metabolic process; valine catabolic process; mitochondrial matrix;
ACAT1	5	small molecule metabolic process; branched-chain amino acid catabolic process; cellular nitrogen compound metabolic process; mitochondrial matrix; mitochondrion;
AUH	5	small molecule metabolic process; branched-chain amino acid catabolic process; cellular nitrogen compound metabolic process; mitochondrial matrix; mitochondrion;

Genes shared at least 2 KEGG pathways with HIBADH (count: 5)

Gene Symbol	Pathway Count	Pathway List
ACAD8	2	Metabolic pathways; Valine, leucine and isoleucine degradation;
ACAT1	2	Metabolic pathways; Valine, leucine and isoleucine degradation;
ALDH3A2	2	Metabolic pathways; Valine, leucine and isoleucine degradation;
AUH	2	Metabolic pathways; Valine, leucine and isoleucine degradation;
ECHS1	2	Metabolic pathways; Valine, leucine and isoleucine degradation;

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Region: chr7:27565059..27702620 View in gBrowse