ADHDgene Database
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  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0004930
Name G-protein coupled receptor activity
Type Molecular Function
No. of Genes in ADHDgene  236
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 236)

Literature-origin genes (count: 12)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
OXER1 oxoeicosanoid (OXE) receptor 1 2p22.1 1(0/0/1) NAS[12065583]
GRM8 glutamate receptor, metabotropic 8 7q31.3-q32.1 1(1/0/0) TAS[9473604]
OR4C3 olfactory receptor, family 4, subfamily C, member 3 11p11.2 1(0/0/1)
TAAR3 trace amine associated receptor 3 (gene/pseudogene) 6q23-q24 1(0/1/0) TAS[10684976]
GPR50 G protein-coupled receptor 50 Xq28 1(0/0/1)
GPR125 G protein-coupled receptor 125 4p15.31 1(0/1/0)
MTNR1B melatonin receptor 1B 11q21-q22 1(0/0/1) TAS[7568007]
GRM1 glutamate receptor, metabotropic 1 6q24 1(1/0/0) TAS[7476890]
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E 6q14-q15 2(2/0/0) TAS[1733778]
GRM5 glutamate receptor, metabotropic 5 11q14.3 2(1/0/1) TAS[7908515]
LPHN3 latrophilin 3 4q13.1 4(3/0/1) NAS[10994649]
OPRM1 opioid receptor, mu 1 6q24-q25 1(1/0/0)

Genes from other sources Help (count: 224)

Approved Symbol Approved Name Source Evidence[PMID]
OR52E4 olfactory receptor, family 52, subfamily E, member 4 Mapped by CNV
RXFP3 relaxin/insulin-like family peptide receptor 3 Mapped by significant region TAS[10806363]
TAAR9 trace amine associated receptor 9 (gene/pseudogene) Mapped by significant region TAS[15718104]
OR52E5 olfactory receptor, family 52, subfamily E, member 5 Mapped by CNV
GPR123 G protein-coupled receptor 123 Mapped by CNV NAS[17212699]
OR52E6 olfactory receptor, family 52, subfamily E, member 6 Mapped by CNV
OR52E8 olfactory receptor, family 52, subfamily E, member 8 Mapped by CNV
OR4S2 olfactory receptor, family 4, subfamily S, member 2 Mapped by significant region
OR4X1 olfactory receptor, family 4, subfamily X, member 1 Mapped by LD-proxy
OR4X2 olfactory receptor, family 4, subfamily X, member 2 Mapped by LD-proxy
OR52B2 olfactory receptor, family 52, subfamily B, member 2 Mapped by CNV
OR4M2 olfactory receptor, family 4, subfamily M, member 2 Mapped by significant region
OR4N4 olfactory receptor, family 4, subfamily N, member 4 Mapped by significant region
GPBAR1 G protein-coupled bile acid receptor 1 Mapped by significant region
OR4P4 olfactory receptor, family 4, subfamily P, member 4 Mapped by significant region
OR4S1 olfactory receptor, family 4, subfamily S, member 1 Mapped by LD-proxy
OR4D11 olfactory receptor, family 4, subfamily D, member 11 Mapped by significant region
OR4D5 olfactory receptor, family 4, subfamily D, member 5 Mapped by significant region
CXCR5 chemokine (C-X-C motif) receptor 5 Mapped by significant region TAS[1425907]
OR4D6 olfactory receptor, family 4, subfamily D, member 6 Mapped by significant region
OR4D9 olfactory receptor, family 4, subfamily D, member 9 Mapped by significant region
OR4C5 olfactory receptor, family 4, subfamily C, member 5 Mapped by LD-proxy; Mapped by literature SNP
OR4C45 olfactory receptor, family 4, subfamily C, member 45 Mapped by LD-proxy
OR4D10 olfactory receptor, family 4, subfamily D, member 10 Mapped by significant region
OR4C6 olfactory receptor, family 4, subfamily C, member 6 Mapped by significant region
OR4C15 olfactory receptor, family 4, subfamily C, member 15 Mapped by significant region
OR4C12 olfactory receptor, family 4, subfamily C, member 12 Mapped by CNV
CXCR1 chemokine (C-X-C motif) receptor 1 Mapped by significant region TAS[8381837]
OR4C16 olfactory receptor, family 4, subfamily C, member 16 Mapped by significant region
OR4A47 olfactory receptor, family 4, subfamily A, member 47 Mapped by LD-proxy
TAAR1 trace amine associated receptor 1 Mapped by significant region TAS[15718104]
TAAR2 trace amine associated receptor 2 Mapped by significant region TAS[15718104]
OR4A16 olfactory receptor, family 4, subfamily A, member 16 Mapped by significant region
OR4C11 olfactory receptor, family 4, subfamily C, member 11 Mapped by significant region
LPAR1 lysophosphatidic acid receptor 1 Mapped by significant region TAS[8922387]
OR4B1 olfactory receptor, family 4, subfamily B, member 1 Mapped by LD-proxy
OR2W5 olfactory receptor, family 2, subfamily W, member 5 Mapped by CNV
TAAR5 trace amine associated receptor 5 Mapped by significant region TAS[15718104]
TAAR6 trace amine associated receptor 6 Mapped by significant region TAS[15718104]
OR2W3 olfactory receptor, family 2, subfamily W, member 3 Mapped by CNV
OR4A15 olfactory receptor, family 4, subfamily A, member 15 Mapped by significant region
OR2Y1 olfactory receptor, family 2, subfamily Y, member 1 Mapped by CNV
TAAR8 trace amine associated receptor 8 Mapped by significant region TAS[15718104]
OR9I1 olfactory receptor, family 9, subfamily I, member 1 Mapped by significant region
OR2T8 olfactory receptor, family 2, subfamily T, member 8 Mapped by CNV
OR9G4 olfactory receptor, family 9, subfamily G, member 4 Mapped by significant region
OR2V1 olfactory receptor, family 2, subfamily V, member 1 Mapped by CNV
OR9G1 olfactory receptor, family 9, subfamily G, member 1 Mapped by significant region
OR2T12 olfactory receptor, family 2, subfamily T, member 12 Mapped by CNV
OR8U1 olfactory receptor, family 8, subfamily U, member 1 Mapped by CNV; Mapped by significant region
OR2T33 olfactory receptor, family 2, subfamily T, member 33 Mapped by CNV
OR2M4 olfactory receptor, family 2, subfamily M, member 4 Mapped by CNV
OR8K5 olfactory receptor, family 8, subfamily K, member 5 Mapped by CNV; Mapped by significant region
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) Mapped by CNV NAS[10907856]
OR8K3 olfactory receptor, family 8, subfamily K, member 3 Mapped by CNV; Mapped by significant region
OR2M5 olfactory receptor, family 2, subfamily M, member 5 Mapped by CNV
OR2M2 olfactory receptor, family 2, subfamily M, member 2 Mapped by CNV
OR8K1 olfactory receptor, family 8, subfamily K, member 1 Mapped by CNV; Mapped by significant region
OR2M3 olfactory receptor, family 2, subfamily M, member 3 Mapped by CNV
OR8J3 olfactory receptor, family 8, subfamily J, member 3 Mapped by CNV; Mapped by significant region
S1PR3 sphingosine-1-phosphate receptor 3 Mapped by significant region TAS[10555146]
BAI3 brain-specific angiogenesis inhibitor 3 Mapped by significant region
OR2L8 olfactory receptor, family 2, subfamily L, member 8 Mapped by CNV
OR2L2 olfactory receptor, family 2, subfamily L, member 2 Mapped by CNV
OR2L3 olfactory receptor, family 2, subfamily L, member 3 Mapped by CNV
APLNR apelin receptor Mapped by significant region
OR2L13 olfactory receptor, family 2, subfamily L, member 13 Mapped by CNV
OR2G3 olfactory receptor, family 2, subfamily G, member 3 Mapped by CNV
OR9Q2 olfactory receptor, family 9, subfamily Q, member 2 Mapped by significant region
OR2K2 olfactory receptor, family 2, subfamily K, member 2 Mapped by significant region
GPRC6A G protein-coupled receptor, family C, group 6, member A Mapped by CNV; Mapped by significant region
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 Mapped by significant region
OR8G1 olfactory receptor, family 8, subfamily G, member 1 Mapped by significant region
OR2G2 olfactory receptor, family 2, subfamily G, member 2 Mapped by CNV
OR2D3 olfactory receptor, family 2, subfamily D, member 3 Mapped by CNV
GPRC5C G protein-coupled receptor, family C, group 5, member C Mapped by CNV
OR8D2 olfactory receptor, family 8, subfamily D, member 2 Mapped by significant region
OR8D4 olfactory receptor, family 8, subfamily D, member 4 Mapped by significant region
OR2D2 olfactory receptor, family 2, subfamily D, member 2 Mapped by CNV
GPRC5B G protein-coupled receptor, family C, group 5, member B Mapped by significant region
GPR83 G protein-coupled receptor 83 Mapped by significant region TAS[10760605]
OR8B8 olfactory receptor, family 8, subfamily B, member 8 Mapped by significant region
OR2C3 olfactory receptor, family 2, subfamily C, member 3 Mapped by CNV
GPR52 G protein-coupled receptor 52 Mapped by significant region
OR8D1 olfactory receptor, family 8, subfamily D, member 1 Mapped by significant region
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 Mapped by significant region
OR8B3 olfactory receptor, family 8, subfamily B, member 3 Mapped by significant region
OR2AK2 olfactory receptor, family 2, subfamily AK, member 2 Mapped by CNV
OR8B4 olfactory receptor, family 8, subfamily B, member 4 Mapped by significant region
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 Mapped by CNV
OR2AG2 olfactory receptor, family 2, subfamily AG, member 2 Mapped by CNV
GPR148 G protein-coupled receptor 148 Mapped by CNV; Mapped by significant region
GPR152 G protein-coupled receptor 152 Mapped by significant region
OR8J1 olfactory receptor, family 8, subfamily J, member 1 Mapped by CNV; Mapped by significant region
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 Mapped by CNV
OR8J2 olfactory receptor, family 8, subfamily J, member 2 (gene/pseudogene) Mapped by CNV; Mapped by significant region
GPR21 G protein-coupled receptor 21 Mapped by significant region
OR2A4 olfactory receptor, family 2, subfamily A, member 4 Mapped by significant region
GPR144 G protein-coupled receptor 144 Mapped by significant region
OR8H3 olfactory receptor, family 8, subfamily H, member 3 Mapped by CNV; Mapped by significant region
OR1S2 olfactory receptor, family 1, subfamily S, member 2 Mapped by significant region
MRGPRF MAS-related GPR, member F Mapped by CNV; Mapped by significant region
OR8I2 olfactory receptor, family 8, subfamily I, member 2 Mapped by CNV; Mapped by significant region
OR1S1 olfactory receptor, family 1, subfamily S, member 1 Mapped by significant region
OR8H1 olfactory receptor, family 8, subfamily H, member 1 Mapped by CNV; Mapped by significant region
MRGPRD MAS-related GPR, member D Mapped by CNV; Mapped by significant region
OR8H2 olfactory receptor, family 8, subfamily H, member 2 Mapped by CNV; Mapped by significant region
GPR142 G protein-coupled receptor 142 Mapped by CNV
OR1Q1 olfactory receptor, family 1, subfamily Q, member 1 Mapped by significant region
OR8G2 olfactory receptor, family 8, subfamily G, member 2 Mapped by significant region
OR1N2 olfactory receptor, family 1, subfamily N, member 2 Mapped by significant region
NPVF neuropeptide VF precursor Mapped by CNV; Mapped by significant region
NPY neuropeptide Y Mapped by CNV; Mapped by significant region TAS[1321422]
OR8G5 olfactory receptor, family 8, subfamily G, member 5 Mapped by significant region
OR1N1 olfactory receptor, family 1, subfamily N, member 1 Mapped by significant region
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 Mapped by LD-proxy TAS[10894923]
OR1J2 olfactory receptor, family 1, subfamily J, member 2 Mapped by significant region
OR5R1 olfactory receptor, family 5, subfamily R, member 1 Mapped by CNV; Mapped by significant region
OR1J4 olfactory receptor, family 1, subfamily J, member 4 Mapped by significant region
OR5P3 olfactory receptor, family 5, subfamily P, member 3 Mapped by CNV
OR1K1 olfactory receptor, family 1, subfamily K, member 1 Mapped by significant region
OR5T2 olfactory receptor, family 5, subfamily T, member 2 Mapped by CNV; Mapped by significant region
OR1L1 olfactory receptor, family 1, subfamily L, member 1 Mapped by significant region
OR5T1 olfactory receptor, family 5, subfamily T, member 1 Mapped by CNV; Mapped by significant region
OR1L3 olfactory receptor, family 1, subfamily L, member 3 Mapped by significant region
OR5W2 olfactory receptor, family 5, subfamily W, member 2 Mapped by CNV; Mapped by significant region
OR1L4 olfactory receptor, family 1, subfamily L, member 4 Mapped by significant region
OR5T3 olfactory receptor, family 5, subfamily T, member 3 Mapped by CNV; Mapped by significant region
OR1L6 olfactory receptor, family 1, subfamily L, member 6 Mapped by significant region
OR1L8 olfactory receptor, family 1, subfamily L, member 8 Mapped by significant region
OR6A2 olfactory receptor, family 6, subfamily A, member 2 Mapped by CNV
OR13D1 olfactory receptor, family 13, subfamily D, member 1 Mapped by significant region
OR6M1 olfactory receptor, family 6, subfamily M, member 1 Mapped by significant region
CASR calcium-sensing receptor Mapped by PBA pathway
OR13F1 olfactory receptor, family 13, subfamily F, member 1 Mapped by significant region
OR6F1 olfactory receptor, family 6, subfamily F, member 1 Mapped by CNV
OR13G1 olfactory receptor, family 13, subfamily G, member 1 Mapped by CNV
OR6T1 olfactory receptor, family 6, subfamily T, member 1 Mapped by significant region
OR14A16 olfactory receptor, family 14, subfamily A, member 16 Mapped by CNV
OR6Q1 olfactory receptor, family 6, subfamily Q, member 1 Mapped by significant region
OR8A1 olfactory receptor, family 8, subfamily A, member 1 Mapped by significant region
OR1B1 olfactory receptor, family 1, subfamily B, member 1 Mapped by significant region
OR6X1 olfactory receptor, family 6, subfamily X, member 1 Mapped by significant region
OR1C1 olfactory receptor, family 1, subfamily C, member 1 Mapped by CNV
OR8B2 olfactory receptor, family 8, subfamily B, member 2 Mapped by significant region
OR1J1 olfactory receptor, family 1, subfamily J, member 1 Mapped by significant region
OR8B12 olfactory receptor, family 8, subfamily B, member 12 Mapped by significant region
XPR1 xenotropic and polytropic retrovirus receptor 1 Mapped by significant region TAS[9990033]
OR11L1 olfactory receptor, family 11, subfamily L, member 1 Mapped by CNV
OR5D14 olfactory receptor, family 5, subfamily D, member 14 Mapped by CNV; Mapped by significant region
OR10W1 olfactory receptor, family 10, subfamily W, member 1 Mapped by significant region
OR5D16 olfactory receptor, family 5, subfamily D, member 16 Mapped by CNV; Mapped by significant region
OR13C3 olfactory receptor, family 13, subfamily C, member 3 Mapped by significant region
OR5D18 olfactory receptor, family 5, subfamily D, member 18 Mapped by CNV; Mapped by significant region
OR13C2 olfactory receptor, family 13, subfamily C, member 2 Mapped by significant region
OR5F1 olfactory receptor, family 5, subfamily F, member 1 Mapped by CNV; Mapped by significant region
OR13C5 olfactory receptor, family 13, subfamily C, member 5 Mapped by significant region
OR5G3 olfactory receptor, family 5, subfamily G, member 3 (gene/pseudogene) Mapped by significant region
OR13C4 olfactory receptor, family 13, subfamily C, member 4 Mapped by significant region
OR5I1 olfactory receptor, family 5, subfamily I, member 1 Mapped by CNV; Mapped by significant region
OR13C9 olfactory receptor, family 13, subfamily C, member 9 Mapped by significant region
OR13C8 olfactory receptor, family 13, subfamily C, member 8 Mapped by significant region
OR5J2 olfactory receptor, family 5, subfamily J, member 2 Mapped by CNV; Mapped by significant region
OR5L1 olfactory receptor, family 5, subfamily L, member 1 Mapped by CNV; Mapped by significant region
OR10G6 olfactory receptor, family 10, subfamily G, member 6 Mapped by significant region
OR5L2 olfactory receptor, family 5, subfamily L, member 2 Mapped by CNV; Mapped by significant region
NTSR2 neurotensin receptor 2 Mapped by significant region TAS[9851594]
OR10G4 olfactory receptor, family 10, subfamily G, member 4 Mapped by significant region
OR5M1 olfactory receptor, family 5, subfamily M, member 1 Mapped by CNV; Mapped by significant region
OR10G8 olfactory receptor, family 10, subfamily G, member 8 Mapped by significant region
OR5M10 olfactory receptor, family 5, subfamily M, member 10 Mapped by CNV; Mapped by significant region
OR10G7 olfactory receptor, family 10, subfamily G, member 7 Mapped by significant region
OR5M11 olfactory receptor, family 5, subfamily M, member 11 Mapped by CNV; Mapped by significant region
OR10Q1 olfactory receptor, family 10, subfamily Q, member 1 Mapped by significant region
OR5M3 olfactory receptor, family 5, subfamily M, member 3 Mapped by CNV; Mapped by significant region
OR10G9 olfactory receptor, family 10, subfamily G, member 9 Mapped by significant region
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 Mapped by significant region TAS[8670200]
OR5M8 olfactory receptor, family 5, subfamily M, member 8 Mapped by CNV; Mapped by significant region
OR10V1 olfactory receptor, family 10, subfamily V, member 1 Mapped by significant region
OR5M9 olfactory receptor, family 5, subfamily M, member 9 Mapped by CNV; Mapped by significant region
OR10S1 olfactory receptor, family 10, subfamily S, member 1 Mapped by significant region
OR5AK3P olfactory receptor, family 5, subfamily AK, member 3 pseudogene Mapped by significant region
OR10A4 olfactory receptor, family 10, subfamily A, member 4 Mapped by CNV
OR5AK2 olfactory receptor, family 5, subfamily AK, member 2 Mapped by significant region
OR10A5 olfactory receptor, family 10, subfamily A, member 5 Mapped by CNV
OR10A3 olfactory receptor, family 10, subfamily A, member 3 Mapped by CNV
OR5A2 olfactory receptor, family 5, subfamily A, member 2 Mapped by significant region
OR5A1 olfactory receptor, family 5, subfamily A, member 1 Mapped by significant region
OR10D3 olfactory receptor, family 10, subfamily D, member 3 (non-functional) Mapped by significant region
OR5AR1 olfactory receptor, family 5, subfamily AR, member 1 Mapped by CNV; Mapped by significant region
OR10D4P olfactory receptor, family 10, subfamily D, member 4 pseudogene Mapped by significant region
OR5AP2 olfactory receptor, family 5, subfamily AP, member 2 Mapped by CNV; Mapped by significant region
OR10A6 olfactory receptor, family 10, subfamily A, member 6 Mapped by CNV
OR5AN1 olfactory receptor, family 5, subfamily AN, member 1 Mapped by significant region
OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 Mapped by CNV; Mapped by significant region
OR5AL1 olfactory receptor, family 5, subfamily AL, member 1 (gene/pseudogene) Mapped by CNV; Mapped by significant region
OR5B2 olfactory receptor, family 5, subfamily B, member 2 Mapped by significant region
OR5B17 olfactory receptor, family 5, subfamily B, member 17 Mapped by significant region
C3AR1 complement component 3a receptor 1 Mapped by PBA pathway IGI[10571060]
OR5B12 olfactory receptor, family 5, subfamily B, member 12 Mapped by significant region
OR5AS1 olfactory receptor, family 5, subfamily AS, member 1 Mapped by CNV; Mapped by significant region
OR5D13 olfactory receptor, family 5, subfamily D, member 13 Mapped by CNV; Mapped by significant region
OR5C1 olfactory receptor, family 5, subfamily C, member 1 Mapped by significant region
OR10A2 olfactory receptor, family 10, subfamily A, member 2 Mapped by CNV
OR5B3 olfactory receptor, family 5, subfamily B, member 3 Mapped by significant region
GRM6 glutamate receptor, metabotropic 6 Mapped by CNV TAS[9215706]
OR5B21 olfactory receptor, family 5, subfamily B, member 21 Mapped by significant region
OR52M1 olfactory receptor, family 52, subfamily M, member 1 Mapped by CNV
OR52N1 olfactory receptor, family 52, subfamily N, member 1 Mapped by CNV
OR52L1 olfactory receptor, family 52, subfamily L, member 1 Mapped by CNV
OR52L2P olfactory receptor, family 52, subfamily L, member 2 pseudogene Mapped by CNV
FZD4 frizzled family receptor 4 Mapped by significant region
OR52N5 olfactory receptor, family 52, subfamily N, member 5 Mapped by CNV
OR52P1P olfactory receptor, family 52, subfamily P, member 1 pseudogene Mapped by CNV
OR52N2 olfactory receptor, family 52, subfamily N, member 2 Mapped by CNV
OR52N4 olfactory receptor, family 52, subfamily N, member 4 Mapped by CNV
OR56A3 olfactory receptor, family 56, subfamily A, member 3 Mapped by CNV
OR56A4 olfactory receptor, family 56, subfamily A, member 4 Mapped by CNV
OR52W1 olfactory receptor, family 52, subfamily W, member 1 Mapped by CNV
OR56A1 olfactory receptor, family 56, subfamily A, member 1 Mapped by CNV
OR56B2P olfactory receptor, family 56, subfamily B, member 2 pseudogene Mapped by CNV
OR56B4 olfactory receptor, family 56, subfamily B, member 4 Mapped by CNV
OR56A5 olfactory receptor, family 56, subfamily A, member 5 Mapped by CNV
OR56B1 olfactory receptor, family 56, subfamily B, member 1 Mapped by CNV

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014