ADHDgene Database

Gene Report

Basic Info

Approved Symbol	OXER1
Symbol Alias	GPCR, TG1019, GPR170
Approved Name	oxoeicosanoid (OXE) receptor 1
Name Alias	5-oxo-ETE acid G-protein-coupled receptor 1
Location	2p22.1
Position	chr2:42989639-42991401, -
External Links	HGNC: 24884 Entrez Gene: 165140 Ensembl: ENSG00000162881 UCSC: uc002rss.2
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008	2 flanking SNPs of this gene with P-value<1E-5.	Trend

Gene related SNPs (count: 9)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs6719977	Chr2:42985803(Fwd)	downstream_gene_variant	1(0/0/1)
rs930421	Chr2:42981239(Fwd)	3_prime_UTR_variant; downstream_gene_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs2278584	Chr2:42989744(Fwd)	3_prime_UTR_variant; downstream_gene_variant
rs11681208	Chr2:42987268(Fwd)	downstream_gene_variant
rs2278582	Chr2:42989444(Fwd)	downstream_gene_variant
rs1992286	Chr2:42990336(Fwd)	downstream_gene_variant; synonymous_variant
rs4953653	Chr2:42989159(Fwd)	downstream_gene_variant
rs7566714	Chr2:42984707(Fwd)	downstream_gene_variant
rs965374	Chr2:42993166(Fwd)	downstream_gene_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030817	regulation of cAMP biosynthetic process	Biological Process	IDA[12065583]	1
GO:0050646	5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Molecular Function	NAS[12065583]	1
GO:0050647	5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Molecular Function	NAS[12065583]	1
GO:0050648	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Molecular Function	NAS[12065583]	1
GO:0004930	G-protein coupled receptor activity	Molecular Function	NAS[12065583]	236
GO:0005886	plasma membrane	Cellular Component		772
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	NAS[12065583]	72
GO:0016021	integral to membrane	Cellular Component		845

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with OXER1 (count: 0)

Genes shared at least 2 KEGG pathways with OXER1 (count: 0)

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Region: chr2:42989639..42991401 View in gBrowse