ADHDgene Database

SNP Report

Basic Info

Name	rs6719977 dbSNP Ensembl
Location	chr2:42985803(Fwd)
Variant Alleles	T/C
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000378661; ENST00000405592; ENST00000406652; ENST00000409019; ENST00000467925)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=1.67E-06 under Additive model for FBAT-PC HI symptom...... P-value=1.67E-06 under Additive model for FBAT-PC HI symptoms More...	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
OXER1	oxoeicosanoid (OXE) receptor 1	2p22.1	1(0/0/1)

Approved Symbol	Approved Name	Location
MTA3	metastasis associated 1 family, member 3	2p22.1

SNPs in LD with rs6719977 (count: 16) View in gBrowse (chr2:42969270..42993166 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs1971138	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.941[CHB]; 0.809[JPT]
rs4953653	downstream_gene_variant	0.918[CEU]; 0.837[CHB]; 0.807[JPT]
rs7566714	downstream_gene_variant	1.0[CEU]; 0.941[CHB]; 0.868[JPT]; 0.937[GIH]
rs6544595	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.932[CHB]; 0.809[JPT]
rs2278584	3_prime_UTR_variant; downstream_gene_variant	0.918[CEU]; 0.883[CHB]; 0.868[JPT]
rs4953631	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.941[CHB]; 0.868[JPT]
rs6713059	intron_variant; nc_transcript_variant; NMD_transcript_variant	1.0[CHB]
rs7591304	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.936[CHB]; 0.868[JPT]
rs965374	downstream_gene_variant; upstream_gene_variant	0.887[CHB]; 0.867[JPT]
rs4953636	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.941[CHB]; 0.809[JPT]
rs2278582	downstream_gene_variant	0.918[CEU]; 0.932[TSI]; 0.887[CHB]; 0.868[JPT]; 0.851[GIH]
rs6544594	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.917[CHB]
rs1016607	intron_variant; nc_transcript_variant; NMD_transcript_variant	0.941[CHB]; 0.809[JPT]
rs2289355	3_prime_UTR_variant; downstream_gene_variant	0.878[CEU]; 0.941[CHB]; 0.809[JPT]
rs7578904	downstream_gene_variant	0.88[CEU]
rs1992286	downstream_gene_variant; synonymous_variant	0.918[CEU]; 0.887[CHB]; 0.858[JPT]