ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MBOAT2
Previous Symbol	OACT2
Symbol Alias	FLJ14415, FLJ90298
Approved Name	membrane bound O-acyltransferase domain containing 2
Previous Name	O-acyltransferase (membrane bound) domain containing 2
Location	2p25
Position	chr2:8992820-9143942, -
External Links	HGNC: 25193 Entrez Gene: 129642 Ensembl: ENSG00000143797 UCSC: uc002qzg.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2p25.1	chr2:7100000-12200000	2 (1/0/1)

Gene related GO terms (count: 8)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 8)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005789	endoplasmic reticulum membrane	Cellular Component	140
GO:0006644	phospholipid metabolic process	Biological Process	59
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	Molecular Function	1
GO:0036152	phosphatidylethanolamine acyl-chain remodeling	Biological Process	15
GO:0044281	small molecule metabolic process	Biological Process	248
GO:0016021	integral to membrane	Cellular Component	845
GO:0036151	phosphatidylcholine acyl-chain remodeling	Biological Process	15
GO:0046474	glycerophospholipid biosynthetic process	Biological Process	30

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa01100	Metabolic pathways	237
hsa00561	Glycerolipid metabolism	15
hsa00564	Glycerophospholipid metabolism	22

Genes shared at least 5 GO terms with MBOAT2 (count: 20)

Gene Symbol	Pathway Count	Pathway List
LPCAT4	7	endoplasmic reticulum membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; integral to membrane; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PNPLA8	7	endoplasmic reticulum membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; integral to membrane; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
LPCAT1	6	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
MBOAT1	6	endoplasmic reticulum membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
PLA2G2A	6	endoplasmic reticulum membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G4C	6	endoplasmic reticulum membrane; phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G16	6	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; integral to membrane; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
CDIPT	5	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
DGAT2	5	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
PEMT	5	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
PLD3	5	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
PNPLA3	5	endoplasmic reticulum membrane; phospholipid metabolic process; small molecule metabolic process; integral to membrane; glycerophospholipid biosynthetic process;
PLA2G10	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G1B	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G2D	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G2E	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G3	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G4B	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G5	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;
PLA2G6	5	phospholipid metabolic process; phosphatidylethanolamine acyl-chain remodeling; small molecule metabolic process; phosphatidylcholine acyl-chain remodeling; glycerophospholipid biosynthetic process;

Genes shared at least 2 KEGG pathways with MBOAT2 (count: 29)

Gene Symbol	Pathway Count	Pathway List
DGKH	3	Metabolic pathways; Glycerolipid metabolism; Glycerophospholipid metabolism;
GPAT2	3	Metabolic pathways; Glycerolipid metabolism; Glycerophospholipid metabolism;
MBOAT1	3	Metabolic pathways; Glycerolipid metabolism; Glycerophospholipid metabolism;
ALDH3A2	2	Metabolic pathways; Glycerolipid metabolism;
CDIPT	2	Metabolic pathways; Glycerophospholipid metabolism;
CHKA	2	Metabolic pathways; Glycerophospholipid metabolism;
DAK	2	Metabolic pathways; Glycerolipid metabolism;
DGAT2	2	Metabolic pathways; Glycerolipid metabolism;
LIPF	2	Metabolic pathways; Glycerolipid metabolism;
LIPG	2	Metabolic pathways; Glycerolipid metabolism;
LPCAT1	2	Metabolic pathways; Glycerophospholipid metabolism;
LPCAT4	2	Metabolic pathways; Glycerophospholipid metabolism;
MGLL	2	Metabolic pathways; Glycerolipid metabolism;
PEMT	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G10	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G1B	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G2A	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G2D	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G2E	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G3	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G4B	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G5	2	Metabolic pathways; Glycerophospholipid metabolism;
PLA2G6	2	Metabolic pathways; Glycerophospholipid metabolism;
PLD1	2	Metabolic pathways; Glycerophospholipid metabolism;
PLD2	2	Metabolic pathways; Glycerophospholipid metabolism;
PNLIP	2	Metabolic pathways; Glycerolipid metabolism;
PNLIPRP1	2	Metabolic pathways; Glycerolipid metabolism;
PNLIPRP2	2	Metabolic pathways; Glycerolipid metabolism;
PNPLA3	2	Metabolic pathways; Glycerolipid metabolism;

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Region: chr2:8992820..9143942 View in gBrowse