ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LIPG
Symbol Alias	EDL
Approved Name	lipase, endothelial
Location	18q21.1
Position	chr18:47087069-47119272, 1
External Links	HGNC: 6623 Entrez Gene: 9388 Ensembl: ENSG00000101670 UCSC: uc002ldv.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0055091	phospholipid homeostasis	biological process	IMP[19136670]	3
GO:0004620	phospholipase activity	molecular function	IDA[10192396]	4
GO:0004465	lipoprotein lipase activity	molecular function	IEA	3
GO:0032376	positive regulation of cholesterol transport	biological process	IDA[19136670]	1
GO:0007584	response to nutrient	biological process	IEA	18
GO:0008970	phosphatidylcholine 1-acylhydrolase activity	molecular function	IDA[10318835]	3
GO:0042632	cholesterol homeostasis	biological process	IMP[19136670]	17
GO:0034375	high-density lipoprotein particle remodeling	biological process	IMP[19136670]	5
GO:0010983	positive regulation of high-density lipoprotein particle clearance	biological process	IMP[19136670]	1
GO:0050746	regulation of lipoprotein metabolic process	biological process	IEA	1
GO:0004806	triglyceride lipase activity	molecular function	IEA	10
GO:0009395	phospholipid catabolic process	biological process	NAS[19136670]	4
GO:0006629	lipid metabolic process	biological process	TAS[10318835]	51
GO:0043691	reverse cholesterol transport	biological process	IMP[19136670]	7
GO:0008201	heparin binding	molecular function	IEA	28
GO:0005615	extracellular space	cellular component	IDA[10192396]	133
GO:0050253	retinyl-palmitate esterase activity	molecular function	IEA	9
GO:0008283	cell proliferation	biological process	IEA	66

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00561	Glycerolipid metabolism	15

Genes shared at least 5 GO terms with LIPG (count: 5)

Gene Symbol	Pathway Count	Pathway List
APOA1	7	phospholipid homeostasis; response to nutrient; cholesterol homeostasis; high-density lipoprotein particle remodeling; lipid metabolic process; reverse cholesterol transport; extracellular space;
PNLIPRP2	6	phospholipase activity; triglyceride lipase activity; phospholipid catabolic process; lipid metabolic process; extracellular space; retinyl-palmitate esterase activity;
LPL	6	phospholipase activity; lipoprotein lipase activity; triglyceride lipase activity; lipid metabolic process; heparin binding; extracellular space;
APOC3	6	response to nutrient; cholesterol homeostasis; high-density lipoprotein particle remodeling; lipid metabolic process; reverse cholesterol transport; extracellular space;
APOA4	5	cholesterol homeostasis; high-density lipoprotein particle remodeling; lipid metabolic process; reverse cholesterol transport; extracellular space;

Genes shared at least 2 KEGG pathways with LIPG (count: 0)

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Region: chr18:47087069..47119272 View in gBrowse