ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04510
Name Focal adhesion
No. of Genes in ADHDgene  40
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 40)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0)
ITGA1 integrin, alpha 1 5q11.1 2(0/2/0)
ITGA11 integrin, alpha 11 15q22.3-q23 1(0/0/1)
FLNC filamin C, gamma 7q32-q35 1(0/0/1)

Genes from other sources Help(count: 35)

Approved Symbol Approved Name Location Source
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
ARHGAP5 Rho GTPase activating protein 5 14q12 Mapped by significant region
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 16p11.2 Mapped by CNV
LAMC2 laminin, gamma 2 1q25-q31 Mapped by significant region
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2p24 Mapped by significant region
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 5q11.2 Mapped by LD-proxy
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 17q11.2-q12 Mapped by LD-proxy
BIRC2 baculoviral IAP repeat containing 2 11q22 Mapped by significant region
BCAR1 breast cancer anti-estrogen resistance 1 16q22-q23 Mapped by significant region
FN1 fibronectin 1 2q34 Mapped by significant region
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 9q22.1 Mapped by significant region
VEGFB vascular endothelial growth factor B 11q13 Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
CCND1 cyclin D1 11q13 Mapped by significant region
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 20p12 Mapped by CNV
BIRC3 baculoviral IAP repeat containing 3 11q22 Mapped by significant region
LAMA2 laminin, alpha 2 6q22-q23 Mapped by CNV; Mapped by significant region
CCND3 cyclin D3 6p21 Mapped by CNV
LAMC1 laminin, gamma 1 (formerly LAMB2) 1q31 Mapped by significant region
ILK integrin-linked kinase 11p15.4 Mapped by CNV
MAPK9 mitogen-activated protein kinase 9 5q35 Mapped by CNV
PDPK1 3-phosphoinositide dependent protein kinase-1 16p13.3 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 22q11.21 Mapped by CNV
ACTN3 actinin, alpha 3 (gene/pseudogene) 11q13.2 Mapped by significant region
BAD BCL2-associated agonist of cell death 11q13.1 Mapped by significant region
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22 Mapped by CNV
CAV3 caveolin 3 3p25 Mapped by Literature SNP
TNC tenascin C 9q33.1 Mapped by significant region
LAMA3 laminin, alpha 3 18q11.2 Mapped by significant region
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 11q13-q14 Mapped by significant region
PDGFD platelet derived growth factor D 11q22.3 Mapped by significant region
TNR tenascin R 1q24 Mapped by significant region
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 11q13 Mapped by significant region
TNN tenascin N 1q23-q24 Mapped by significant region