ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003714
Name transcription corepressor activity
Type molecular function
No. of Genes in ADHDgene  33
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 33)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
MEIS2 Meis homeobox 2 15q14 1(0/0/1) TAS[10764806]
NFIL3 nuclear factor, interleukin 3 regulated 9q22 2(1/1/0) TAS[1620116]
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2p16.1 1(0/0/1) IEA
TLE4 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) 9q21.32 1(1/0/0) IEA
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) TAS[2194290]
TDP2 tyrosyl-DNA phosphodiesterase 2 6p22.3-p22.1 1(0/1/0) TAS[10764746]
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 6p12 1(1/0/0) IDA[7559606]
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 2(2/0/0) IDA[12933792]

Genes from other sources Help (count: 25)

Approved Symbol Approved Name Source Evidence[PMID]
SCAI suppressor of cancer cell invasion Mapped by significant region IMP[19350017]
NRIP1 nuclear receptor interacting protein 1 Mapped by PBA pathway IDA[10364267]
NPAT nuclear protein, ataxia-telangiectasia locus Mapped by CNV; Mapped by significant region IMP[17163457]
JAZF1 JAZF zinc finger 1 Mapped by significant region IDA[15302918]
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway IDA[12466272]
CRYM crystallin, mu Mapped by significant region IMP[11897713]
HSBP1 heat shock factor binding protein 1 Mapped by CNV; Mapped by significant region TAS[9649501]
TRIM22 tripartite motif containing 22 Mapped by CNV TAS[7797467]
SF1 splicing factor 1 Mapped by significant region; Mapped by PBA pathway TAS[9660765]
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) Mapped by significant region IEA
LHX1 LIM homeobox 1 Mapped by CNV ISS
SNW1 SNW domain containing 1 Mapped by PBA pathway IDA[14985122]
FEV FEV (ETS oncogene family) Mapped by significant region TAS[9121764]
HIRA histone cell cycle regulator Mapped by CNV TAS[9731536]
BASP1 brain abundant, membrane attached signal protein 1 Mapped by significant region IMP[14701728]
SKOR1 SKI family transcriptional corepressor 1 Mapped by LD-proxy IEA
YAP1 Yes-associated protein 1 Mapped by significant region IDA[18158288]
E4F1 E4F transcription factor 1 Mapped by significant region TAS[10869426]
E2F6 E2F transcription factor 6 Mapped by significant region TAS[9501179]
KCTD1 potassium channel tetramerization domain containing 1 Mapped by significant region IDA[19115315]
NEUROD2 neuronal differentiation 2 Mapped by LD-proxy ISS
NCOR2 nuclear receptor corepressor 2 Mapped by CNV IDA[18052923]; IMP[12628926]
NSD1 nuclear receptor binding SET domain protein 1 Mapped by PBA pathway ISS
SAP18 Sin3A-associated protein, 18kDa Mapped by significant region TAS[9150135]
RCOR2 REST corepressor 2 Mapped by significant region IEA