ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0003714
Name	transcription corepressor activity
Type	Molecular Function
No. of Genes in ADHDgene	29
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 29)

Literature-origin genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
MEIS2	Meis homeobox 2	15q14	1(0/0/1)	TAS[10764806]
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	12q23	2(2/0/0)	IDA[12933792]
NFIL3	nuclear factor, interleukin 3 regulated	9q22	2(1/1/0)	TAS[1620116]
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)	TAS[2194290]
TDP2	tyrosyl-DNA phosphodiesterase 2	6p22.3-p22.1	1(0/1/0)	TAS[10764746]
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2p16.1	1(0/0/1)

Genes from other sources (count: 23)

Approved Symbol	Approved Name	Source	Evidence[PMID]
DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)	Mapped by significant region
NCOR2	nuclear receptor corepressor 2	Mapped by CNV	IDA[18052923]; IMP[12628926]
NSD1	nuclear receptor binding SET domain protein 1	Mapped by PBA pathway
CRYM	crystallin, mu	Mapped by significant region	IMP[11897713]
YAP1	Yes-associated protein 1	Mapped by significant region	IDA[18158288]
NRIP1	nuclear receptor interacting protein 1	Mapped by PBA pathway	IDA[10364267]
SCAI	suppressor of cancer cell invasion	Mapped by significant region	IMP[19350017]
NPAT	nuclear protein, ataxia-telangiectasia locus	Mapped by CNV; Mapped by significant region	IMP[17163457]
E2F6	E2F transcription factor 6	Mapped by significant region	TAS[9501179]
JAZF1	JAZF zinc finger 1	Mapped by significant region	IDA[15302918]
NCOR1	nuclear receptor corepressor 1	Mapped by significant region	IDA[18052923]; IMP[15695367]
NEUROD2	neurogenic differentiation 2	Mapped by LD-proxy
KCTD1	potassium channel tetramerisation domain containing 1	Mapped by significant region	IDA[19115315]
HSBP1	heat shock factor binding protein 1	Mapped by CNV; Mapped by significant region	TAS[9649501]
LHX1	LIM homeobox 1	Mapped by CNV
SF1	splicing factor 1	Mapped by PBA pathway; Mapped by significant region	TAS[9660765]
HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)	Mapped by CNV	TAS[9731536]
SNW1	SNW domain containing 1	Mapped by PBA pathway	IDA[14985122]
RCOR2	REST corepressor 2	Mapped by significant region
FEV	FEV (ETS oncogene family)	Mapped by significant region	TAS[9121764]
SAP18	Sin3A-associated protein, 18kDa	Mapped by significant region	TAS[9150135]
TRIM22	tripartite motif containing 22	Mapped by CNV	TAS[7797467]
DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	Mapped by PBA pathway	IDA[12466272]