ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0000209
Name	protein polyubiquitination
Type	Biological Process
No. of Genes in ADHDgene	23
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	6q25.2-q27	1(1/0/0)	IDA[16227987]
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)
TRIM32	tripartite motif containing 32	9q33.1	1(0/0/1)	IDA[18632609]

Genes from other sources (count: 20)

Approved Symbol	Approved Name	Source	Evidence[PMID]
SKP2	S-phase kinase-associated protein 2 (p45)	Mapped by significant region
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	Mapped by significant region
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	Mapped by significant region
PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	Mapped by significant region	IDA[11435423]
G2E3	G2/M-phase specific E3 ubiquitin protein ligase	Mapped by significant region
UBC	ubiquitin C	Mapped by CNV
RNF31	ring finger protein 31	Mapped by significant region	IDA[17006537]
BIRC2	baculoviral IAP repeat containing 2	Mapped by significant region	IDA[11907583]
BLMH	bleomycin hydrolase	Mapped by CNV; Mapped by LD-proxy
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	Mapped by significant region	IDA[18077552]
RNF20	ring finger protein 20	Mapped by significant region	IDA[19037095]
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	Mapped by CNV	IDA[12732143]
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	Mapped by significant region
FBXO4	F-box protein 4	Mapped by significant region
UBB	ubiquitin B	Mapped by significant region
UBOX5	U-box domain containing 5	Mapped by CNV
PSMA8	proteasome (prosome, macropain) subunit, alpha type, 8	Mapped by significant region
UBE4A	ubiquitination factor E4A	Mapped by significant region
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	Mapped by significant region
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	Mapped by significant region