ADHDgene Database
  • Hot Results
  • Quick Search
Keyword:
Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0048011
Name nerve growth factor receptor signaling pathway
Type Biological Process
No. of Genes in ADHDgene  42
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 42)

Literature-origin genes (count: 8)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1)
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0)
NET1 neuroepithelial cell transforming 1 10p15 0
FURIN furin (paired basic amino acid cleaving enzyme) 15q26.1 1(0/0/1)
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 1(1/0/0)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)
TRIO triple functional domain (PTPRF interacting) 5p14-p15.1 1(0/0/1)

Genes from other sources Help (count: 34)

Approved Symbol Approved Name Source Evidence[PMID]
KIDINS220 kinase D-interacting substrate, 220kDa Mapped by significant region
UBC ubiquitin C Mapped by CNV
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by LD-proxy; Mapped by literature SNP
RIT2 Ras-like without CAAX 2 Mapped by significant region
MAPKAP1 mitogen-activated protein kinase associated protein 1 Mapped by significant region
RICTOR RPTOR independent companion of MTOR, complex 2 Mapped by significant region
AATF apoptosis antagonizing transcription factor Mapped by CNV
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 Mapped by significant region
RTN4 reticulon 4 Mapped by CNV
SORT1 sortilin 1 Mapped by CNV IMP[14985763]
RTN4R reticulon 4 receptor Mapped by CNV
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mapped by significant region
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 Mapped by PBA pathway
FGD3 FYVE, RhoGEF and PH domain containing 3 Mapped by significant region
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) Mapped by PBA pathway
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV
SQSTM1 sequestosome 1 Mapped by CNV
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region
MCF2L MCF.2 cell line derived transforming sequence-like Mapped by CNV
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV
ADCY4 adenylate cyclase 4 Mapped by significant region
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 Mapped by significant region
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 Mapped by CNV; Mapped by significant region
ADORA2A adenosine A2a receptor Mapped by CNV
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region
BAD BCL2-associated agonist of cell death Mapped by significant region
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 Mapped by significant region
MAPK7 mitogen-activated protein kinase 7 Mapped by significant region
NDN necdin homolog (mouse) Mapped by CNV; Mapped by significant region
UBB ubiquitin B Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014