ADHDgene Database

Gene Report

Basic Info

Approved Symbol	KIDINS220
Symbol Alias	ARMS
Approved Name	kinase D-interacting substrate, 220kDa
Name Alias	ankyrin repeat-rich membrane-spanning protein
Location	2p24
Position	chr2:8865408-8977760, -
External Links	HGNC: 29508 Entrez Gene: 57498 Ensembl: ENSG00000134313 UCSC: uc002qzc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
2p25.1	chr2:7100000-12200000	2 (1/0/1)

Gene related GO terms (count: 6)

ID	Name	Type	No. of Genes in ADHDgene
GO:0016021	integral to membrane	Cellular Component	845
GO:0048011	nerve growth factor receptor signaling pathway	Biological Process	42
GO:0048813	dendrite morphogenesis	Biological Process	8
GO:0005829	cytosol	Cellular Component	447
GO:0001701	in utero embryonic development	Biological Process	32
GO:0000186	activation of MAPKK activity	Biological Process	9

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04722	Neurotrophin signaling pathway	24	Neurotrophins are a family of trophic factors involved in di...... Neurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin 3 (NT-3), and neurotrophin 4 (NT-4). Neurotrophins exert their functions through engagement of Trk tyrosine kinase receptors or p75 neurotrophin receptor (p75NTR). Neurotrophin/Trk signaling is regulated by connecting a variety of intracellular signaling cascades, which include MAPK pathway, PI-3 kinase pathway, and PLC pathway, transmitting positive signals like enhanced survival and growth. On the other hand, p75NTR transmits both positive and nagative signals. These signals play an important role for neural development and additional higher-order activities such as learning and memory. More...

Genes shared at least 5 GO terms with KIDINS220 (count: 0)

Genes shared at least 2 KEGG pathways with KIDINS220 (count: 0)

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Region: chr2:8865408..8977760 View in gBrowse