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- Data Summary
GO Report
Basic Info
| ID | GO:0045471 |
|---|---|
| Name | response to ethanol |
| Type | Biological Process |
| No. of Genes in ADHDgene | 17 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 17)
Literature-origin genes (count: 9)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CNR1 | cannabinoid receptor 1 (brain) | 6q14-q15 | 1(1/0/0) | |
| DRD3 | dopamine receptor D3 | 3q13.3 | 8(1/7/0) | |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 6q13 | 13(5/8/0) | |
| MAOB | monoamine oxidase B | Xp11.4-p11.3 | 6(2/4/0) | |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 12p12 | 1(1/0/0) | IDA[18445116] |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 16p13.2 | 3(1/2/0) | IDA[18445116] |
| NPPC | natriuretic peptide C | 2q24-qter | 1(0/1/0) | |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 5p15.3 | 68(42/25/1) | |
| TH | tyrosine hydroxylase | 11p15.5 | 7(2/5/0) | IDA[18343820] |
Genes from other sources (count: 8)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| GRIN3A | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | Mapped by significant region | IDA[18445116] |
| AACS | acetoacetyl-CoA synthetase | Mapped by CNV | |
| CCND1 | cyclin D1 | Mapped by significant region | |
| OXCT1 | 3-oxoacid CoA transferase 1 | Mapped by significant region | |
| GSN | gelsolin | Mapped by PBA pathway; Mapped by significant region | |
| TJP1 | tight junction protein 1 (zona occludens 1) | Mapped by CNV; Mapped by significant region | |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 | Mapped by CNV | |
| BAD | BCL2-associated agonist of cell death | Mapped by significant region |