ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0016567
Name	protein ubiquitination
Type	Biological Process
No. of Genes in ADHDgene	41
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 41)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ARRB1	arrestin, beta 1	11q13	2(1/1/0)	IMP[15878855]
TRIM32	tripartite motif containing 32	9q33.1	1(0/0/1)	IDA[16816390]
ARRB2	arrestin, beta 2	17p13	1(1/0/0)	IMP[15878855]

Genes from other sources (count: 38)

Approved Symbol	Approved Name	Source	Evidence[PMID]
ZBTB16	zinc finger and BTB domain containing 16	Mapped by significant region
UBA6	ubiquitin-like modifier activating enzyme 6	Mapped by significant region	IMP[17889673]
WWP1	WW domain containing E3 ubiquitin protein ligase 1	Mapped by CNV	TAS[12535537]
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	Mapped by significant region	NAS[11244092]
PLK1	polo-like kinase 1	Mapped by significant region	IDA[16885022]
KLHL7	kelch-like 7 (Drosophila)	Mapped by significant region
RCHY1	ring finger and CHY zinc finger domain containing 1	Mapped by CNV	IDA[19043414]
FBXO4	F-box protein 4	Mapped by significant region	IDA[10531035]
MKRN3	makorin ring finger protein 3	Mapped by CNV; Mapped by significant region
HERC2	hect domain and RLD 2	Mapped by significant region
RNF25	ring finger protein 25	Mapped by significant region
RFWD3	ring finger and WD repeat domain 3	Mapped by significant region
PELI3	pellino homolog 3 (Drosophila)	Mapped by significant region
BIRC6	baculoviral IAP repeat containing 6	Mapped by CNV	TAS[18329369]
FBXO31	F-box protein 31	Mapped by significant region
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	Mapped by significant region	IDA[15125833]
SYVN1	synovial apoptosis inhibitor 1, synoviolin	Mapped by significant region
RNF169	ring finger protein 169	Mapped by significant region
FBXO25	F-box protein 25	Mapped by CNV	NAS[10531035]
RFWD2	ring finger and WD repeat domain 2	Mapped by significant region
NEUROD2	neurogenic differentiation 2	Mapped by LD-proxy
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Mapped by significant region	TAS[15465819]
CUL5	cullin 5	Mapped by PBA pathway; Mapped by significant region
GAN	gigaxonin	Mapped by significant region	IDA[15983046]
BARD1	BRCA1 associated RING domain 1	Mapped by significant region	NAS[15905410]
TRIM22	tripartite motif containing 22	Mapped by CNV
RNF19A	ring finger protein 19A	Mapped by PBA pathway
ASB15	ankyrin repeat and SOCS box containing 15	Mapped by CNV
KLHL36	kelch-like 36 (Drosophila)	Mapped by CNV; Mapped by significant region
KLHL22	kelch-like 22 (Drosophila)	Mapped by CNV
RNF144A	ring finger protein 144A	Mapped by significant region
FBXW2	F-box and WD repeat domain containing 2	Mapped by significant region	TAS[10531035]
TRIP12	thyroid hormone receptor interactor 12	Mapped by PBA pathway
DTX4	deltex homolog 4 (Drosophila)	Mapped by significant region
RNF138	ring finger protein 138	Mapped by significant region
KLHL20	kelch-like 20 (Drosophila)	Mapped by significant region
CRBN	cereblon	Mapped by CNV
KCTD13	potassium channel tetramerisation domain containing 13	Mapped by CNV	IDA[19782033]