ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0016567
Name protein ubiquitination
Type biological process
No. of Genes in ADHDgene  48
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 48)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TRIM32 tripartite motif containing 32 9q33.1 1(0/0/1) IDA[16816390]
ARRB1 arrestin, beta 1 11q13 2(1/1/0) IMP[15878855]
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IMP[15878855]

Genes from other sources Help (count: 45)

Approved Symbol Approved Name Source Evidence[PMID]
FBXO25 F-box protein 25 Mapped by CNV ISS; NAS[10531035]
FBXL7 F-box and leucine-rich repeat protein 7 Mapped by significant region ISS
RAB40C RAB40C, member RAS oncogene family Mapped by significant region IEA
RNF169 ring finger protein 169 Mapped by significant region IEA
BARD1 BRCA1 associated RING domain 1 Mapped by significant region NAS[15905410]
FBXO4 F-box protein 4 Mapped by significant region IDA[10531035]
SOCS1 suppressor of cytokine signaling 1 Mapped by significant region IEA
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Mapped by significant region NAS[11244092]
MARCH11 membrane-associated ring finger (C3HC4) 11 Mapped by significant region IEA
SYVN1 synovial apoptosis inhibitor 1, synoviolin Mapped by significant region IEA
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IDA[15125833]
RFWD3 ring finger and WD repeat domain 3 Mapped by significant region IDA
MKRN3 makorin ring finger protein 3 Mapped by CNV; Mapped by significant region IEA
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 Mapped by significant region IDA
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase Mapped by significant region IDA[14743216]
E4F1 E4F transcription factor 1 Mapped by significant region IEA
KLHL7 kelch-like family member 7 Mapped by significant region IDA; IEA
CCNF cyclin F Mapped by significant region IDA
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase Mapped by CNV IDA[19043414]
CUL5 cullin 5 Mapped by significant region; Mapped by PBA pathway IEA
TRIM22 tripartite motif containing 22 Mapped by CNV IEA
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region TAS[15465819]
CRBN cereblon Mapped by CNV IEA; IMP
GAN gigaxonin Mapped by significant region IDA[15983046]; IEA
DTX4 deltex 4, E3 ubiquitin ligase Mapped by significant region IEA
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase Mapped by PBA pathway IEA
KCTD13 potassium channel tetramerization domain containing 13 Mapped by CNV IDA[19782033]
FBXW2 F-box and WD repeat domain containing 2 Mapped by significant region TAS[10531035]
KLHL20 kelch-like family member 20 Mapped by significant region IDA
FBXO31 F-box protein 31 Mapped by significant region IEA
RNF25 ring finger protein 25 Mapped by significant region ISS
TRIP12 thyroid hormone receptor interactor 12 Mapped by PBA pathway NAS
NEUROD2 neuronal differentiation 2 Mapped by LD-proxy ISS
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Mapped by significant region IEA
KLHL22 kelch-like family member 22 Mapped by CNV IEA
PELI3 pellino E3 ubiquitin protein ligase family member 3 Mapped by significant region IEA
RNF138 ring finger protein 138, E3 ubiquitin protein ligase Mapped by significant region IEA
KLHL36 kelch-like family member 36 Mapped by CNV; Mapped by significant region IEA
UBA6 ubiquitin-like modifier activating enzyme 6 Mapped by significant region IEA; IMP[17889673]
UNKL unkempt family zinc finger-like Mapped by significant region IEA
BIRC6 baculoviral IAP repeat containing 6 Mapped by CNV TAS[18329369]
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 Mapped by significant region IEA
PLK1 polo-like kinase 1 Mapped by significant region IDA[16885022]
ASB15 ankyrin repeat and SOCS box containing 15 Mapped by CNV IEA
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IEA