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- Data Summary
GO Report
Basic Info
| ID | GO:0014069 |
|---|---|
| Name | postsynaptic density |
| Type | Cellular Component |
| No. of Genes in ADHDgene | 23 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 23)
Literature-origin genes (count: 11)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 12p12 | 1(1/0/0) | |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 7q21 | 1(0/0/1) | |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 1(1/0/0) | |
| GRM5 | glutamate receptor, metabotropic 5 | 11q14.3 | 2(1/0/1) | |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 16p13.2 | 3(1/2/0) | |
| DRD2 | dopamine receptor D2 | 11q22-q23 | 10(3/7/0) | |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 12p13.3 | 1(0/1/0) | IDA[14140941] |
| LIN7C | lin-7 homolog C (C. elegans) | 11p14 | 1(1/0/0) | |
| GRM1 | glutamate receptor, metabotropic 1 | 6q24 | 1(1/0/0) | |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 | 15q24 | 1(0/1/0) | |
| ARRB2 | arrestin, beta 2 | 17p13 | 1(1/0/0) |
Genes from other sources (count: 12)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| ARHGAP32 | Rho GTPase activating protein 32 | Mapped by significant region | |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | Mapped by significant region | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| MTMR2 | myotubularin related protein 2 | Mapped by significant region | |
| NLGN1 | neuroligin 1 | Mapped by CNV | TAS[15797875] |
| DLG2 | discs, large homolog 2 (Drosophila) | Mapped by significant region | |
| P2RX6 | purinergic receptor P2X, ligand-gated ion channel, 6 | Mapped by CNV | |
| CACNG5 | calcium channel, voltage-dependent, gamma subunit 5 | Mapped by PBA pathway | |
| GRIN3A | glutamate receptor, ionotropic, N-methyl-D-aspartate 3A | Mapped by significant region | |
| CHRM1 | cholinergic receptor, muscarinic 1 | Mapped by PBA pathway; Mapped by significant region | |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | Mapped by significant region | |
| CNIH2 | cornichon homolog 2 (Drosophila) | Mapped by significant region |