Hot Results
- Quick Search
- Large-scale studies
- Genome-wide Association Studies of ADHD
- Genome-wide Linkage Studies of ADHD
- Genome-wide CNV Analyses of ADHD
- Meta-analysis Studies of ADHD
- Data Summary
GO Report
Basic Info
| ID | GO:0007269 |
|---|---|
| Name | neurotransmitter secretion |
| Type | Biological Process |
| No. of Genes in ADHDgene | 18 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 18)
Literature-origin genes (count: 14)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| SYT2 | synaptotagmin II | 1q32.1 | 1(1/0/0) | |
| SYN3 | synapsin III | 22q12.3 | 1(0/1/0) | |
| SLC18A2 | solute carrier family 18 (vesicular monoamine), member 2 | 10q25 | 2(0/2/0) | |
| SLC5A7 | solute carrier family 5 (choline transporter), member 7 | 2q12 | 1(1/0/0) | |
| NRXN1 | neurexin 1 | 2p16.3 | 1(0/1/0) | |
| CPLX1 | complexin 1 | 4p16.3 | 1(1/0/0) | |
| LIN7C | lin-7 homolog C (C. elegans) | 11p14 | 1(1/0/0) | |
| STX1A | syntaxin 1A (brain) | 7q11.2 | 3(2/1/0) | |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) | 17pter-p12 | 2(0/2/0) | |
| SYT1 | synaptotagmin I | 12cen-q21 | 4(2/2/0) | |
| SNPH | syntaphilin | 20p13 | 1(1/0/0) | NAS[10707983] |
| MAOA | monoamine oxidase A | Xp11.4-p11.3 | 20(13/7/0) | |
| SNAP25 | synaptosomal-associated protein, 25kDa | 20p12-p11.2 | 18(13/5/0) | |
| SLC6A1 | solute carrier family 6 (neurotransmitter transporter, GABA), member 1 | 3p25-p24 | 1(0/1/0) |
Genes from other sources (count: 4)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| RAB14 | RAB14, member RAS oncogene family | Mapped by PBA pathway; Mapped by significant region | |
| SYT4 | synaptotagmin IV | Mapped by significant region | |
| NRXN2 | neurexin 2 | Mapped by significant region | |
| HSPA8 | heat shock 70kDa protein 8 | Mapped by significant region |