ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007166
Name	cell surface receptor signaling pathway
Type	Biological Process
No. of Genes in ADHDgene	35
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 35)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
TDP2	tyrosyl-DNA phosphodiesterase 2	6p22.3-p22.1	1(0/1/0)	TAS[10764746]
OXTR	oxytocin receptor	3p25	1(0/1/0)	TAS[1313946]
ADRB2	adrenergic, beta-2-, receptor, surface	5q31-q32	2(1/1/0)	TAS[1371121]

Genes from other sources (count: 32)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PRLR	prolactin receptor	Mapped by significant region	NAS[10585417]
CCKBR	cholecystokinin B receptor	Mapped by CNV; Mapped by PBA pathway	NAS[10913157]
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	Mapped by CNV	TAS[9382880]
CD3D	CD3d molecule, delta (CD3-TCR complex)	Mapped by significant region	IC[9485181]
CCR5	chemokine (C-C motif) receptor 5	Mapped by PBA pathway	TAS[8639485]
GP1BB	glycoprotein Ib (platelet), beta polypeptide	Mapped by CNV	NAS[3353370]
IL7R	interleukin 7 receptor	Mapped by significant region	TAS[9843216]
CABIN1	calcineurin binding protein 1	Mapped by CNV	NAS[9655484]
IGSF6	immunoglobulin superfamily, member 6	Mapped by significant region	TAS[9809579]
TRPV1	transient receptor potential cation channel, subfamily V, member 1	Mapped by PBA pathway	TAS[9349813]
BDKRB2	bradykinin receptor B2	Mapped by PBA pathway	TAS[7916737]
C5	complement component 5	Mapped by significant region	TAS[10820279]
CXCR1	chemokine (C-X-C motif) receptor 1	Mapped by significant region	IDA[10734056]
IRF9	interferon regulatory factor 9	Mapped by significant region	TAS[1630447]
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	Mapped by significant region
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mapped by CNV	IDA[12782713]
IL17C	interleukin 17C	Mapped by significant region	TAS[10639155]
NTSR2	neurotensin receptor 2	Mapped by significant region	TAS[9851594]
CLCF1	cardiotrophin-like cytokine factor 1	Mapped by significant region
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	Mapped by significant region	NAS[12110186]
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	Mapped by significant region	TAS[15465819]
NUP62	nucleoporin 62kDa	Mapped by PBA pathway	IDA[10799545]; NAS[10373430]
INHA	inhibin, alpha	Mapped by significant region	TAS[12456957]
BIRC3	baculoviral IAP repeat containing 3	Mapped by significant region	TAS[8548810]
BIRC2	baculoviral IAP repeat containing 2	Mapped by significant region	TAS[8548810]
LIFR	leukemia inhibitory factor receptor alpha	Mapped by significant region	TAS[1915266]
OSMR	oncostatin M receptor	Mapped by significant region	TAS[8999038]
CXCR2	chemokine (C-X-C motif) receptor 2	Mapped by significant region	IDA[10734056]
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	Mapped by LD-proxy	IDA[9685399]
CD3G	CD3g molecule, gamma (CD3-TCR complex)	Mapped by significant region	IMP[12407027]
SPN	sialophorin	Mapped by CNV
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	Mapped by significant region	TAS[9311921]