ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007166
Name cell surface receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  36
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 36)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TDP2 tyrosyl-DNA phosphodiesterase 2 6p22.3-p22.1 1(0/1/0) TAS[10764746]
OXTR oxytocin receptor 3p25 1(0/1/0) TAS[1313946]
ADRB2 adrenoceptor beta 2, surface 5q31-q32 2(1/1/0) TAS[1371121]

Genes from other sources Help (count: 33)

Approved Symbol Approved Name Source Evidence[PMID]
CD3E CD3e molecule, epsilon (CD3-TCR complex) Mapped by significant region NAS[12110186]
SPN sialophorin Mapped by CNV IEA
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) Mapped by PBA pathway TAS[8639485]
IRF9 interferon regulatory factor 9 Mapped by significant region TAS[1630447]
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B Mapped by significant region TAS[9311921]
CD3D CD3d molecule, delta (CD3-TCR complex) Mapped by significant region IC[9485181]
LIFR leukemia inhibitory factor receptor alpha Mapped by significant region TAS[1915266]
CABIN1 calcineurin binding protein 1 Mapped by CNV NAS[9655484]
GP1BB glycoprotein Ib (platelet), beta polypeptide Mapped by CNV NAS[3353370]
NTSR2 neurotensin receptor 2 Mapped by significant region TAS[9851594]
BIRC3 baculoviral IAP repeat containing 3 Mapped by significant region TAS[8548810]
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway TAS[9349813]
C5 complement component 5 Mapped by significant region TAS[10820279]
IL7R interleukin 7 receptor Mapped by significant region TAS[9843216]
CXCR1 chemokine (C-X-C motif) receptor 1 Mapped by significant region IDA[10734056]
IL17C interleukin 17C Mapped by significant region TAS[10639155]
PRLR prolactin receptor Mapped by significant region NAS[10585417]
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region IDA[10734056]
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region TAS[15465819]
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein Mapped by significant region ISS
NUP62 nucleoporin 62kDa Mapped by PBA pathway IDA[10799545]; ISS; NAS[10373430]
GIPR gastric inhibitory polypeptide receptor Mapped by LD-proxy TAS[7556958]
CLCF1 cardiotrophin-like cytokine factor 1 Mapped by significant region ISS
IGSF6 immunoglobulin superfamily, member 6 Mapped by significant region TAS[9809579]
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) Mapped by CNV IDA[12782713]
BDKRB2 bradykinin receptor B2 Mapped by PBA pathway TAS[7916737]
CCKBR cholecystokinin B receptor Mapped by CNV; Mapped by PBA pathway NAS[10913157]
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy IDA[9685399]
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 Mapped by CNV TAS[9382880]
INHA inhibin, alpha Mapped by significant region TAS[12456957]
CD3G CD3g molecule, gamma (CD3-TCR complex) Mapped by significant region IMP[12407027]
OSMR oncostatin M receptor Mapped by significant region TAS[8999038]
BIRC2 baculoviral IAP repeat containing 2 Mapped by significant region TAS[8548810]