ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0051092
Name	positive regulation of NF-kappaB transcription factor activity
Type	Biological Process
No. of Genes in ADHDgene	27
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 27)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
TRIM32	tripartite motif containing 32	9q33.1	1(0/0/1)

Genes from other sources (count: 26)

Approved Symbol	Approved Name	Source	Evidence[PMID]
PLA2G1B	phospholipase A2, group IB (pancreas)	Mapped by PBA pathway	ISS[15528384]
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	Mapped by CNV	IDA[9367155]; IMP[12296995]
UBC	ubiquitin C	Mapped by CNV
RIPK3	receptor-interacting serine-threonine kinase 3	Mapped by significant region
IL6	interleukin 6 (interferon, beta 2)	Mapped by significant region	IDA[12419823]
EDA2R	ectodysplasin A2 receptor	Mapped by CNV	IDA[11039935]
GREM1	gremlin 1	Mapped by CNV; Mapped by significant region
PRKCB	protein kinase C, beta	Mapped by significant region
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	Mapped by significant region	TAS[18508628]
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	Mapped by significant region
TERF2IP	telomeric repeat binding factor 2, interacting protein	Mapped by significant region
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mapped by significant region	IDA[15790681]
INS	insulin	Mapped by literature SNP	IDA[19727662]
TRIM5	tripartite motif containing 5	Mapped by CNV
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Mapped by PBA pathway	IDA[19043560]
ADAM8	ADAM metallopeptidase domain 8	Mapped by CNV; Mapped by LD-proxy
TRAF1	TNF receptor-associated factor 1	Mapped by significant region	IDA[10692572]
PRKD1	protein kinase D1	Mapped by significant region	IMP[12505989]
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	Mapped by significant region	IMP[18223652]
TLR4	toll-like receptor 4	Mapped by significant region	IDA[12594207]
RNF25	ring finger protein 25	Mapped by significant region	IDA[12748188]
ANKRD42	ankyrin repeat domain 42	Mapped by significant region
PYCARD	PYD and CARD domain containing	Mapped by CNV	IDA[12656673]
UBB	ubiquitin B	Mapped by significant region
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	Mapped by significant region	IMP[19509286]
RNF31	ring finger protein 31	Mapped by significant region	IDA[19136968]