ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0003712
Name	transcription cofactor activity
Type	Molecular Function
No. of Genes in ADHDgene	17
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 17)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
HES6	hairy and enhancer of split 6 (Drosophila)	2q37.3	1(0/1/0)	ISS[10851137]
MEIS2	Meis homeobox 2	15q14	1(0/0/1)

Genes from other sources (count: 15)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IDA[12218053]
MED13	mediator complex subunit 13	Mapped by PBA pathway	IDA[12218053]
TADA2A	transcriptional adaptor 2A	Mapped by CNV	TAS[8552087]
MED24	mediator complex subunit 24	Mapped by PBA pathway	IDA[12218053]
NSD1	nuclear receptor binding SET domain protein 1	Mapped by PBA pathway	IDA[11509567]
MED17	mediator complex subunit 17	Mapped by PBA pathway; Mapped by significant region	IDA[12218053]
MED4	mediator complex subunit 4	Mapped by PBA pathway	IDA[12218053]
PTPN14	protein tyrosine phosphatase, non-receptor type 14	Mapped by literature SNP
THRAP3	thyroid hormone receptor associated protein 3	Mapped by PBA pathway	IDA[12218053]
POU2AF1	POU class 2 associating factor 1	Mapped by significant region	TAS[7859290]
MED12	mediator complex subunit 12	Mapped by PBA pathway	IDA[12218053]
MED14	mediator complex subunit 14	Mapped by PBA pathway	IDA[12218053]
MED16	mediator complex subunit 16	Mapped by PBA pathway	IDA[12218053]
MED30	mediator complex subunit 30	Mapped by PBA pathway	IDA[12218053]
LPXN	leupaxin	Mapped by significant region	IDA[18451096]