ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0030168
Name	platelet activation
Type	Biological Process
No. of Genes in ADHDgene	38
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA2B	adrenergic, alpha-2B-, receptor	2q11.1	1(1/0/0)
ARRB1	arrestin, beta 1	11q13	2(1/1/0)
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)
DGKH	diacylglycerol kinase, eta	13q13.3	1(1/0/0)
ARRB2	arrestin, beta 2	17p13	1(1/0/0)
ADRA2C	adrenergic, alpha-2C-, receptor	4p16.3	7(2/4/1)

Genes from other sources (count: 31)

Approved Symbol	Approved Name	Source	Evidence[PMID]
VEGFB	vascular endothelial growth factor B	Mapped by significant region
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
TRPC6	transient receptor potential cation channel, subfamily C, member 6	Mapped by significant region
SYK	spleen tyrosine kinase	Mapped by significant region
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	Mapped by significant region
CFL1	cofilin 1 (non-muscle)	Mapped by significant region
IL6	interleukin 6 (interferon, beta 2)	Mapped by significant region	TAS[7831669]
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	Mapped by LD-proxy; Mapped by literature SNP
MGLL	monoglyceride lipase	Mapped by PBA pathway
FN1	fibronectin 1	Mapped by significant region
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Mapped by CNV
TRPC3	transient receptor potential cation channel, subfamily C, member 3	Mapped by PBA pathway
PRKCB	protein kinase C, beta	Mapped by significant region
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	Mapped by CNV
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	Mapped by significant region
HABP4	hyaluronan binding protein 4	Mapped by significant region
WDR1	WD repeat domain 1	Mapped by CNV
POTEKP	POTE ankyrin domain family, member K, pseudogene	Mapped by significant region
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
APOA1	apolipoprotein A-I	Mapped by significant region
F2RL2	coagulation factor II (thrombin) receptor-like 2	Mapped by PBA pathway
GP1BB	glycoprotein Ib (platelet), beta polypeptide	Mapped by CNV	NAS[12871509]
STX4	syntaxin 4	Mapped by CNV
TUBA4A	tubulin, alpha 4a	Mapped by significant region
DAGLA	diacylglycerol lipase, alpha	Mapped by significant region
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Mapped by significant region
RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	Mapped by significant region
ALDOA	aldolase A, fructose-bisphosphate	Mapped by CNV
STXBP3	syntaxin binding protein 3	Mapped by CNV