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- Data Summary
GO Report
Basic Info
| ID | GO:0008083 |
|---|---|
| Name | growth factor activity |
| Type | Molecular Function |
| No. of Genes in ADHDgene | 25 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 25)
Literature-origin genes (count: 8)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| EREG | epiregulin | 4q21.21 | 1(0/0/1) | |
| NTF3 | neurotrophin 3 | 12p13 | 3(1/2/0) | |
| VEGFA | vascular endothelial growth factor A | 6p12 | 1(0/1/0) | |
| GDNF | glial cell derived neurotrophic factor | 5p13.1-p12 | 2(1/1/0) | |
| BDNF | brain-derived neurotrophic factor | 11p14.1 | 14(8/6/0) | |
| FGF10 | fibroblast growth factor 10 | 5p13-p12 | 1(0/1/0) | IDA[15690149] |
| CNTF | ciliary neurotrophic factor | 11q12 | 1(1/0/0) | IDA[12643274] |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) |
Genes from other sources (count: 17)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| REG1A | regenerating islet-derived 1 alpha | Mapped by CNV | IDA[10526060] |
| IL6 | interleukin 6 (interferon, beta 2) | Mapped by significant region | IDA[2261637] |
| VEGFB | vascular endothelial growth factor B | Mapped by significant region | |
| FGF4 | fibroblast growth factor 4 | Mapped by significant region | |
| OGN | osteoglycin | Mapped by significant region | |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | Mapped by PBA pathway | |
| OSGIN1 | oxidative stress induced growth inhibitor 1 | Mapped by CNV; Mapped by significant region | IDA[11459809] |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | Mapped by LD-proxy; Mapped by literature SNP | IDA[11500939] |
| INHA | inhibin, alpha | Mapped by significant region | TAS[12324653] |
| PDGFD | platelet derived growth factor D | Mapped by significant region | |
| CTGF | connective tissue growth factor | Mapped by significant region | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | Mapped by significant region | IDA[1674604] |
| FGF19 | fibroblast growth factor 19 | Mapped by significant region | |
| FGF3 | fibroblast growth factor 3 | Mapped by significant region | |
| CLCF1 | cardiotrophin-like cytokine factor 1 | Mapped by significant region | TAS[14632778] |
| BTC | betacellulin | Mapped by CNV | |
| FGF9 | fibroblast growth factor 9 (glia-activating factor) | Mapped by significant region |