ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008083
Name growth factor activity
Type molecular function
No. of Genes in ADHDgene  28
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 28)

Literature-origin genes (count: 9)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IDA; ISS
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IDA[15690149]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) IEA
GDNF glial cell derived neurotrophic factor 5p13.1-p12 2(1/1/0) NAS
EREG epiregulin 4q21.21 1(0/0/1) IEA
CNTF ciliary neurotrophic factor 11q12 1(1/0/0) IDA[12643274]
BDNF brain-derived neurotrophic factor 11p14.1 16(8/8/0) IEA
FGF12 fibroblast growth factor 12 3q28 1(0/1/0) IEA
NTF3 neurotrophin 3 12p13 4(1/3/0) IDA

Genes from other sources Help (count: 19)

Approved Symbol Approved Name Source Evidence[PMID]
FGF3 fibroblast growth factor 3 Mapped by significant region IEA
CTGF connective tissue growth factor Mapped by significant region IEA
OGN osteoglycin Mapped by significant region IEA
RABEP2 rabaptin, RAB GTPase binding effector protein 2 Mapped by LD-proxy IEA
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IDA[2261637]
OSGIN1 oxidative stress induced growth inhibitor 1 Mapped by CNV; Mapped by significant region IDA[11459809]
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Mapped by significant region IDA[1674604]
GFER growth factor, augmenter of liver regeneration Mapped by significant region IEA
PDGFD platelet derived growth factor D Mapped by significant region IEA
INHA inhibin, alpha Mapped by significant region TAS[12324653]
IGF2 insulin-like growth factor 2 (somatomedin A) Mapped by LD-proxy IDA[11500939]
FGF19 fibroblast growth factor 19 Mapped by significant region IEA
VEGFB vascular endothelial growth factor B Mapped by significant region IEA
CXCL12 chemokine (C-X-C motif) ligand 12 Mapped by PBA pathway IEA
CLCF1 cardiotrophin-like cytokine factor 1 Mapped by significant region TAS[14632778]
REG1A regenerating islet-derived 1 alpha Mapped by CNV IDA[10526060]
FGF9 fibroblast growth factor 9 Mapped by significant region IEA
FGF4 fibroblast growth factor 4 Mapped by significant region IEA
BTC betacellulin Mapped by CNV IEA