ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008219
Name	cell death
Type	Biological Process
No. of Genes in ADHDgene	33
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 33)

Literature-origin genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	68(42/25/1)
GRM1	glutamate receptor, metabotropic 1	6q24	1(1/0/0)
ATXN1	ataxin 1	6p23	1(0/0/1)
DPP6	dipeptidyl-peptidase 6	7q36.2	1(1/0/0)
ATXN2	ataxin 2	12q23-q24.1	1(0/0/1)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A	13q14-q21	12(6/6/0)
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	6q25.2-q27	1(1/0/0)

Genes from other sources (count: 26)

Approved Symbol	Approved Name	Source	Evidence[PMID]
KIAA0196	KIAA0196	Mapped by CNV
FBXO7	F-box protein 7	Mapped by LD-proxy
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	Mapped by PBA pathway	IDA[16595610]
IGHMBP2	immunoglobulin mu binding protein 2	Mapped by CNV; Mapped by significant region
SPG7	spastic paraplegia 7 (pure and complicated autosomal recessive)	Mapped by significant region
MAP3K11	mitogen-activated protein kinase kinase kinase 11	Mapped by significant region
DBC1	deleted in bladder cancer 1	Mapped by significant region	IDA[14712213]
FA2H	fatty acid 2-hydroxylase	Mapped by significant region
FUS	fused in sarcoma	Mapped by CNV
SPTBN2	spectrin, beta, non-erythrocytic 2	Mapped by significant region
REEP1	receptor accessory protein 1	Mapped by CNV
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	Mapped by CNV	IDA[10891486]
SIGMAR1	sigma non-opioid intracellular receptor 1	Mapped by LD-proxy
TPP1	tripeptidyl peptidase I	Mapped by CNV
NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1	Mapped by significant region
PANK2	pantothenate kinase 2	Mapped by CNV
PLA2G6	phospholipase A2, group VI (cytosolic, calcium-independent)	Mapped by PBA pathway
TARDBP	TAR DNA binding protein	Mapped by literature SNP
PNPLA8	patatin-like phospholipase domain containing 8	Mapped by PBA pathway	IDA[15695510]
GAN	gigaxonin	Mapped by significant region
BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	Mapped by significant region
FOLR1	folate receptor 1 (adult)	Mapped by significant region
NUP62	nucleoporin 62kDa	Mapped by PBA pathway	IMP[11244088]
OPTN	optineurin	Mapped by PBA pathway
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	Mapped by CNV; Mapped by PBA pathway
DAGLA	diacylglycerol lipase, alpha	Mapped by significant region