ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DPP6
Symbol Alias	DPPX
Approved Name	dipeptidyl-peptidase 6
Previous Name	dipeptidylpeptidase VI, "dipeptidylpeptidase 6"
Location	7q36.2
Position	chr7:153584182-154685995, +
External Links	HGNC: 3010 Entrez Gene: 1804 Ensembl: ENSG00000130226 UCSC: uc003wlk.2
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin; Mapped by CNV

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Elia, J., 2012	This gene was found directly affected by CNVRs overrepresented in individuals with ADHD.	Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_89	chr7:153332837-153468471 (NCBI Build 35 (hg17))	135635	7q36.2	Deletion (hemizygous)	Maternal
CNV_Elia[2012]_6	chr7:153495598-153564827 (NCBI36 / hg18)	69230	7q36.2	Dup	1:2:0(100%)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008236	serine-type peptidase activity	Molecular Function		11
GO:0008219	cell death	Biological Process		33
GO:0006508	proteolysis	Biological Process		102
GO:0043266	regulation of potassium ion transport	Biological Process		4
GO:0019228	regulation of action potential in neuron	Biological Process		4
GO:0016021	integral to membrane	Cellular Component		845
GO:0008239	dipeptidyl-peptidase activity	Molecular Function	TAS[8103397]	4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DPP6 (count: 0)

Genes shared at least 2 KEGG pathways with DPP6 (count: 0)

View in gBrowse

Region: chr7:153584182..154685995 View in gBrowse