ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0004872
Name	receptor activity
Type	Molecular Function
No. of Genes in ADHDgene	36
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 36)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
NRXN1	neurexin 1	2p16.3	1(0/1/0)	TAS[1621094]
HTR3A	5-hydroxytryptamine (serotonin) receptor 3A	11q23.1-q23.2	1(0/1/0)	TAS[9950429]

Genes from other sources (count: 34)

Approved Symbol	Approved Name	Source	Evidence[PMID]
EDA2R	ectodysplasin A2 receptor	Mapped by CNV	IDA[11039935]
XPR1	xenotropic and polytropic retrovirus receptor 1	Mapped by significant region	TAS[9988277]
MED13	mediator complex subunit 13	Mapped by PBA pathway	IDA[12218053]
SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	Mapped by CNV
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	Mapped by significant region	TAS[14527427]
MED24	mediator complex subunit 24	Mapped by PBA pathway	IDA[12218053]
NPC1	Niemann-Pick disease, type C1	Mapped by significant region	TAS[9211849]
IL10RA	interleukin 10 receptor, alpha	Mapped by significant region	TAS[8407942]
ATRN	attractin	Mapped by CNV
CHRM3	cholinergic receptor, muscarinic 3	Mapped by CNV; Mapped by PBA pathway	TAS[10940357]
CUBN	cubilin (intrinsic factor-cobalamin receptor)	Mapped by CNV	TAS[10080186]
CUL5	cullin 5	Mapped by PBA pathway; Mapped by significant region	TAS[9581826]
RTN4RL2	reticulon 4 receptor-like 2	Mapped by significant region	IDA[12694398]
MED14	mediator complex subunit 14	Mapped by PBA pathway	IDA[12218053]
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	Mapped by CNV	TAS[9367155]
TMEM123	transmembrane protein 123	Mapped by significant region	NAS[9600958]
RTN4R	reticulon 4 receptor	Mapped by CNV	NAS[11201742]
NLGN1	neuroligin 1	Mapped by CNV
MED17	mediator complex subunit 17	Mapped by PBA pathway; Mapped by significant region	IDA[12218053]
MED4	mediator complex subunit 4	Mapped by PBA pathway	IDA[12218053]
GABRA5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	Mapped by CNV; Mapped by significant region	TAS[1321750]
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IDA[12218053]
FOLR1	folate receptor 1 (adult)	Mapped by significant region	TAS[10633085]
MED12	mediator complex subunit 12	Mapped by PBA pathway	IDA[12218053]
THRAP3	thyroid hormone receptor associated protein 3	Mapped by PBA pathway	IDA[12218053]
APLNR	apelin receptor	Mapped by significant region	TAS[9792798]
TLR4	toll-like receptor 4	Mapped by significant region	TAS[10426995]
P2RY2	purinergic receptor P2Y, G-protein coupled, 2	Mapped by significant region	TAS[7779087]
CD5	CD5 molecule	Mapped by significant region	NAS[1711157]
MED16	mediator complex subunit 16	Mapped by PBA pathway	IDA[12218053]
MED30	mediator complex subunit 30	Mapped by PBA pathway	IDA[12218053]
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	Mapped by significant region	IDA[15613544]
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	Mapped by CNV	TAS[9382880]
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	Mapped by significant region	TAS[9311921]