ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006511
Name ubiquitin-dependent protein catabolic process
Type Biological Process
No. of Genes in ADHDgene  25
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 25)

Literature-origin genes (count: 3)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1)
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 6q25.2-q27 1(1/0/0)
USP24 ubiquitin specific peptidase 24 1p32.3 1(1/0/0)

Genes from other sources Help (count: 22)

Approved Symbol Approved Name Source Evidence[PMID]
UBA6 ubiquitin-like modifier activating enzyme 6 Mapped by significant region IMP[17889673]
FBXO7 F-box protein 7 Mapped by LD-proxy TAS[10531035]
USP46 ubiquitin specific peptidase 46 Mapped by CNV
RNF20 ring finger protein 20 Mapped by significant region IMP[19037095]
USP22 ubiquitin specific peptidase 22 Mapped by significant region
FBXO4 F-box protein 4 Mapped by significant region IDA[16275645]
USP37 ubiquitin specific peptidase 37 Mapped by significant region
USP2 ubiquitin specific peptidase 2 Mapped by significant region
ANAPC4 anaphase promoting complex subunit 4 Mapped by CNV TAS[9469815]
USP41 ubiquitin specific peptidase 41 Mapped by CNV
CUL5 cullin 5 Mapped by PBA pathway; Mapped by significant region
USP35 ubiquitin specific peptidase 35 Mapped by significant region
USP34 ubiquitin specific peptidase 34 Mapped by LD-proxy
UBE3A ubiquitin protein ligase E3A Mapped by CNV; Mapped by significant region TAS[8221889]
SQSTM1 sequestosome 1 Mapped by CNV TAS[8702753]
USP10 ubiquitin specific peptidase 10 Mapped by CNV; Mapped by significant region
USP31 ubiquitin specific peptidase 31 Mapped by significant region
RNF40 ring finger protein 40 Mapped by CNV
USP28 ubiquitin specific peptidase 28 Mapped by significant region
UBE4A ubiquitination factor E4A Mapped by significant region
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 Mapped by significant region TAS[9353319]
UFD1L ubiquitin fusion degradation 1 like (yeast) Mapped by CNV TAS[9063746]

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014