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- Data Summary
GO Report
Basic Info
| ID | GO:0043524 |
|---|---|
| Name | negative regulation of neuron apoptotic process |
| Type | Biological Process |
| No. of Genes in ADHDgene | 19 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 19)
Literature-origin genes (count: 11)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 6q25.2-q27 | 1(1/0/0) | |
| CNTFR | ciliary neurotrophic factor receptor | 9p13 | 1(1/0/0) | |
| ISL1 | ISL LIM homeobox 1 | 5q11.2 | 1(0/1/0) | |
| GDNF | glial cell derived neurotrophic factor | 5p13.1-p12 | 2(1/1/0) | IDA[8493557] |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) | |
| NTF3 | neurotrophin 3 | 12p13 | 3(1/2/0) | |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 2q22-q23 | 2(0/2/0) | |
| CNTF | ciliary neurotrophic factor | 11q12 | 1(1/0/0) | IDA[10966616] |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 4q21.3-q22 | 1(0/1/0) | |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 9q22.1 | 1(1/0/0) | |
| BDNF | brain-derived neurotrophic factor | 11p14.1 | 14(8/6/0) |
Genes from other sources (count: 8)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| CLCF1 | cardiotrophin-like cytokine factor 1 | Mapped by significant region | IDA[11285233] |
| CHL1 | cell adhesion molecule with homology to L1CAM (close homolog of L1) | Mapped by CNV | |
| ADORA2A | adenosine A2a receptor | Mapped by CNV | |
| ADAM8 | ADAM metallopeptidase domain 8 | Mapped by CNV; Mapped by LD-proxy | |
| VEGFB | vascular endothelial growth factor B | Mapped by significant region | IDA[18259607] |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | Mapped by significant region | |
| ILK | integrin-linked kinase | Mapped by CNV | |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | Mapped by PBA pathway |