ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005925
Name	focal adhesion
Type	Cellular Component
No. of Genes in ADHDgene	26
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	17p11.2	2(1/1/0)

Genes from other sources (count: 25)

Approved Symbol	Approved Name	Source	Evidence[PMID]
LIMA1	LIM domain and actin binding 1	Mapped by PBA pathway	IDA[10618726]
NOX4	NADPH oxidase 4	Mapped by significant region
DIXDC1	DIX domain containing 1	Mapped by significant region
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV	TAS[19565474]
SORBS3	sorbin and SH3 domain containing 3	Mapped by PBA pathway	IDA[9885244]
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	Mapped by significant region
FES	feline sarcoma oncogene	Mapped by LD-proxy	IDA[18046454]
BSPRY	B-box and SPRY domain containing	Mapped by significant region
RDX	radixin	Mapped by significant region
ACTN3	actinin, alpha 3	Mapped by significant region	IMP[16807302]
FLII	flightless I homolog (Drosophila)	Mapped by significant region
LAYN	layilin	Mapped by significant region
TNS1	tensin 1	Mapped by significant region
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
RFWD2	ring finger and WD repeat domain 2	Mapped by significant region
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	TAS[19565474]
ADAM17	ADAM metallopeptidase domain 17	Mapped by significant region	IDA[14970227]
GAK	cyclin G associated kinase	Mapped by LD-proxy
TGFB1I1	transforming growth factor beta 1 induced transcript 1	Mapped by PBA pathway
ILK	integrin-linked kinase	Mapped by CNV
LPXN	leupaxin	Mapped by significant region
AATF	apoptosis antagonizing transcription factor	Mapped by CNV
TPPP	tubulin polymerization promoting protein	Mapped by PBA pathway
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	Mapped by significant region
KIF22	kinesin family member 22	Mapped by CNV