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- Data Summary
GO Report
Basic Info
| ID | GO:0007204 |
|---|---|
| Name | elevation of cytosolic calcium ion concentration |
| Type | Biological Process |
| No. of Genes in ADHDgene | 20 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 20)
Literature-origin genes (count: 5)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 12p13.3 | 1(0/1/0) | IDA[12130699] |
| OXTR | oxytocin receptor | 3p25 | 1(0/1/0) | |
| ADRA1A | adrenergic, alpha-1A-, receptor | 8p21.2 | 3(2/1/0) | |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 | 1p13 | 1(1/0/0) | |
| OPRM1 | opioid receptor, mu 1 | 6q24-q25 | 1(1/0/0) |
Genes from other sources (count: 15)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| CCKBR | cholecystokinin B receptor | Mapped by CNV; Mapped by PBA pathway | IDA[10913157] |
| LPAR1 | lysophosphatidic acid receptor 1 | Mapped by significant region | TAS[9804623] |
| TRPC6 | transient receptor potential cation channel, subfamily C, member 6 | Mapped by significant region | |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) | Mapped by PBA pathway | |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | Mapped by PBA pathway | |
| CCR5 | chemokine (C-C motif) receptor 5 | Mapped by PBA pathway | TAS[10201901] |
| PIK3CG | phosphoinositide-3-kinase, catalytic, gamma polypeptide | Mapped by CNV | |
| PLCE1 | phospholipase C, epsilon 1 | Mapped by PBA pathway | TAS[11022047] |
| CAV3 | caveolin 3 | Mapped by LD-proxy; Mapped by literature SNP | |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | Mapped by significant region | |
| S1PR3 | sphingosine-1-phosphate receptor 3 | Mapped by significant region | TAS[9409733] |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | TAS[1849646] |
| BDKRB2 | bradykinin receptor B2 | Mapped by PBA pathway | TAS[10653985] |
| C3AR1 | complement component 3a receptor 1 | Mapped by PBA pathway | IGI[10571060] |
| CCKAR | cholecystokinin A receptor | Mapped by CNV | TAS[8503909] |